Sökning: "INFLAMMATION"

Visar resultat 16 - 20 av 2624 avhandlingar innehållade ordet INFLAMMATION.

1. 16. Prostaglandins and Isoprostanes in Relation to Risk Factors for Atherosclerosis : Role of Inflammation and Oxidative Stress

   Författare :Johanna Helmersson; Samar Basu; Bengt Vessby; Tommy Cederholm; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; prostaglandin F2α; F2-isoprostane; interleukin-6; C-reactive protein; serum amyloid A; tocopherols; cardiovascular risk factors; variation; inflammation; oxidative stress; human; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden;

   Sammanfattning : Inflammation and oxidative stress may be involved in atherogenesis. This thesis describes clinical studies of prostaglandin F2α (PGF2α), an inflammatory mediator, and the isoprostane 8-iso-PGF2α, a reliable indicator of oxidative stress, and cytokine-related inflammatory mediators and indicators in healthy subjects and in a population-based cohort of Swedish men. LÄS MER

3. 17. Multifunctional roles of plasmin in inflammation : Studies of animal models on rheumatoid arthritis, multiple sclerosis, wound healing and infection

   Författare :Jinan Li; Peter Carmeliet; Umeå universitet; []
   Nyckelord :Plasmin; complement; inflammation; wound healing; infection; autoimmune disease; non-autoimmune disease; rheumatoid arthritis; multiple sclerosis; tympanic membrane; otitis media; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : Plasmin has been suggested to be involved in degradation of extracellular matrix (ECM) and tissue remodeling during a number of physiological and pathological processes. The aims of this thesis were to study the functional roles of plasmin during pathological inflammation in autoimmune and nonautoimmune disease models of rheumatoid arthritis (RA), multiple sclerosis (MS), wound healing and infection. LÄS MER

4. 18. Endogenous and microbial modulators of inflammation

   Författare :Jamie D. Kraft; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; Resolution; Specialized pro-resolving mediators; Lipoxins; Neutrophils; Cardiometabolic disease; Next-generation probiotic; Oxygen-tolerance; Faecalibacterium prausnitzii; Desulfovibrio piger; Inter-strain variation;

   Sammanfattning : Cardiometabolic disease is characterized by dysregulated, chronic inflammation, that may result from impaired resolution pathways or alterations in the gut microbiota. Thus, restoring specialized pro-resolving mediators (SPMs) or intestinal bacteria with immunomodulatory properties represent potential therapeutic strategies for patients. LÄS MER

5. 19. Biomarkers of inflammation in atrial fibrillation

   Författare :Julia Aulin; Jonas Oldgren; Ziad Hijazi; Lars Wallentin; Håkan Wallén; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; biomarkers; inflammation; inflammatory biomarkers; oral anticoagulation; heart failure; left ventricular function; ejection fraction; risk assessment; risk prediction; interleukin 6 IL-6 ; C-reactive protein CRP ;

   Sammanfattning : Atrial fibrillation (AF) is common and associated with increased risk of stroke, heart failure (HF) and mortality. Inflammation is linked to AF.The overall aim of this thesis was to investigate inflammatory activity and cardiovascular outcomes and mortality in patients with AF on effective oral anticoagulation. LÄS MER

7. 20. Exploring Links between Melatonin, Inflammation and Depression

   Författare :Isak Sundberg; Janet Cunningham; Lisa Ekselius; Daniel Lindqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melatonin; inflammation; depression; biomarkers; cytokines; anxiety; hepatitis C; Psychiatry; Psykiatri;

   Sammanfattning : Major depressive disorder (MDD) is one of the leading global causes of disease burden. Worse yet, about one third of the patients with MDD do not experience a remission with current treatments. LÄS MER