Sökning: "prostaglandin F2α"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden prostaglandin F2α.
1. A study on the vascular effects of prostaglandin F2α[ and latanaprost in the eye with special reference to the surface hyperaemia after topical administration
Sammanfattning : The ocular hypotensive effect of topically applied prostaglandins is usually accompanied byconjunctival hyperaemia and irritation. The purpose of the present study was to investigate thepharmacological mechanism of the ocular surface hyperaemia induced by topically appliedprostaglandins, particularly prostaglandin F2α (PGF2α) and its synthetic analogue latanoprost, aselective FP prostanoid receptor agonist. LÄS MER
2. Prostaglandins and Isoprostanes in Relation to Risk Factors for Atherosclerosis : Role of Inflammation and Oxidative Stress
Sammanfattning : Inflammation and oxidative stress may be involved in atherogenesis. This thesis describes clinical studies of prostaglandin F2α (PGF2α), an inflammatory mediator, and the isoprostane 8-iso-PGF2α, a reliable indicator of oxidative stress, and cytokine-related inflammatory mediators and indicators in healthy subjects and in a population-based cohort of Swedish men. LÄS MER
3. Prostaglandin E synthases in periodontitis-affected gingival tissue and in gingival fibroblasts
Sammanfattning : Periodontitis is a chronic inflammatory disease resulting in the destruction of the tissue and alveolar bone supporting the teeth and leading ultimately to tooth loss. Prostaglandin E2 (PGE2) is an important inflammatory mediator in the pathogenesis of periodontitis. LÄS MER
4. Receptor-mediated uterine effects of oxytocin and vasopressin
Sammanfattning : The neurohypophyseal hormones oxytocin and vasopressin are important in the regulation of uterine contractility. These hormones, as well as prostaglandin F2α, are most forceful myometrial tissue contractors. LÄS MER
5. Lipid peroxidation in vivo : Evaluation and application of methods for measurement
Sammanfattning : Lipid peroxidation is thought to be an important factor in the pathophysiology of a number of diseases and in the process of ageing, but its measurement in vivo has been difficult. The aim of this thesis was to evaluate methods for measurement of lipid peroxidation in vivo that are suitable for clinical investigations, and to apply these methods in animal and human studies investigating basal conditions and situations associated with increased lipid peroxidation. LÄS MER