Sökning: "HIV-1 infection"

Visar resultat 11 - 15 av 199 avhandlingar innehållade orden HIV-1 infection.

  1. 11. Regulation of HIV-1 mRNA Processing by Cellular Splicing Factors

    Författare :Anna Tranell; Stefan Schwartz; Göran Akusjärvi; Ingemar Ernberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; SR protein; SRp55; SFRS6; splicing; indole derivative; Medical Virology; Medicinsk virologi;

    Sammanfattning : According to UNAIDS there were 34 million people living with human immunodeficiency virus (HIV) infection at the end of 2010. HIV is the causative agent of acquired immunodeficiency syndrome (AIDS) and the number of people dying of AIDS-related causes at the end of 2010 was 1.8 million. LÄS MER

  3. 12. Evolution of HIV-1 coreceptor use in relation to pathogenesis

    Författare :Ingrid Karlsson; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; RANTES; higly active antiretroviral therapy; pathogenesis; lymphoid tissue; cehmokine receptor; biological phenotype; coreceptor; HIV-1; evolution;

    Sammanfattning : HIV-1 uses the coreceptors CCR5 and/or CXCR4 in addition to CD4 to enter the host cell. CCR5-using HIV-1 (R5 phenotype) appears to transmit infection and usually dominates the early stages of disease. LÄS MER

  4. 13. HIV-1 envelope protein gp120. Glycovirology of the V3 loop

    Författare :Britt Losman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AIDS; HIV-1; Carbohydrates; V3-region; V1-region; Coreceptors;

    Sammanfattning : The human immunodeficiency virus type 1 (HIV-1) infection usually is lethal as a consequence of the acquired immunodeficiency syndrome (AIDS). HIV-1 is an enveloped virus and the trimeric envelope glycoprotein complex, gp120/gp41, is responsible for binding of the virus both to the primary cellular receptor CD4 and the coreceptors, CXCR4 and CCR5. LÄS MER

  5. 14. Complement activation - good or evil in HIV-1 infection? : interaction of free and complement opsonized HIV-1 with monocyte derived dendritic cells and immune cells in the cervical mucosa

    Författare :Veronica Tjomsland; Marie Larsson; Jorma Hinkula; Karl-Eric Magnusson; Barbara Shacklett; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Worldwide, the heterosexual route is the most common mode of sexual transmission of HIV-1 and women are particularly susceptible to this infection. After penetration of the mucosal epithelium HIV-1 interacts with potential target cells, i.e. dendritic cells (DCs) and CD4+ T cells. LÄS MER

  7. 15. Plant-produced STI vaccine antigens with special emphasis on HIV-1 p24

    Författare :Ingrid Lindh; Åke Strid; Sören Andersson; Edward Rybicki; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant-based vaccines; Arabidopsis thaliana; HIV-1; p24; GALT; mucosal immunity; Chlamydia trachomatis; MOMP; Daucus carota; Chemistry; Kemi; Chemistry; Kemi;

    Sammanfattning : Objective: To establish stable transgenic non-toxic plants as a platform for plant-based vaccine production as well as potential oral delivery system of vaccine antigens for sexually transmitted infections (STIs). The concept is to immunize the mucosal immune system present in the gut-associated lymphoid tissues (GALT). LÄS MER