Sökning: "mucosal immunity"

Visar resultat 1 - 5 av 81 avhandlingar innehållade orden mucosal immunity.

  1. 1. Mucosal immunity against mycobacterial infection

    Författare :Muhammad Jubayer Rahman; Carmen Fernández; Ingileif Jonsdottir; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucosal immunity; Vaccination; Diagnosis; Mycobacterial infection; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : This thesis aimed to the identification of immune biomarkers of mycobacterial infection for better diagnosis of tuberculosis (TB) and also focused on new vaccination strategies with a particular emphasis on the immune responses in the respiratory tract using murine models. Since the lung is the natural habitat for the M. LÄS MER

  2. 2. Mucosal immunity in the respiratory tract : The role of IgA in protection against intracellular pathogens

    Författare :Ariane Rodríguez; Carmen Fernández; Lennart Hammarström; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunity; respiratory tract; IgA; intracellular pathogens; Immunology; Immunologi;

    Sammanfattning : The lungs and upper airways are mucosal surfaces that are common site for infection with an enormous variety of inhaled pathogens. Therefore, induction of immune responses in the respiratory tract is crucial for protection against respiratory diseases. One of the pathogens infecting the host via the respiratory tract is Mycobacterium Tuberculosis. LÄS MER

  3. 3. IgA Nephropathy – Mucosal Immunity and Treatment Options

    Författare :Hilde Kloster Smerud; Bengt Fellström; Gudjon Kristjansson; Roger Hällgren; Johan W. de Fijter; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA nephropathy; mucosal immunity; gastrointestinal sensitivity; food allergens; pharmacological treatment; budesonide; statin; clinical trial; renal transplantation; recurrence; Internal Medicine; Internmedicin;

    Sammanfattning : In the present studies we have explored the link between food hypersensitivity and IgA nephropathy (IgAN) and evaluated treatment options in primary and recurrent disease. Approximately one third of our IgAN patients had a rectal mucosal sensitivity to gluten, as demonstrated by increased local mucosal nitric oxide production and/or myeloperoxidase release after gluten challenge. LÄS MER

  4. 4. Mucosal Immunity in Mycobacterial infections

    Författare :Anna Tjärnlund; Marita Troye-Blomberg; Andrzej Pawlowski; Anders Örn; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : More than a century after the identification of the tubercle bacillus and the first attempts at vaccination, tuberculosis (TB) still remains one of the world’s most serious infectious diseases. TB, caused by the bacterium Mycobacterium tuberculosis, is typically a disease of the lung, which serves both as port of entry and as the major site of disease manifestation. LÄS MER

  5. 5. Cholera toxin B subunit as a carrier for inducing mucosal immunity and/or peripheral tolerance

    Författare :Carola Rask; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucosal immunity; tolerance; atopic allergy; cholera toxin B subunit; antibody response; IgE;

    Sammanfattning : When an antigen is introduced via a mucosal route, either immunity or tolerance, or even both may be induced. Both immunity and tolerance are actively induced phenomena and both of them could have important medical implications as well as potential prophylactic or therapeutic applications. LÄS MER