Sökning: "disulfide stress"
Visar resultat 1 - 5 av 24 avhandlingar innehållade orden disulfide stress.
1. Bacterial Adaptive Responses - Coping with Oxygen Limitation, Reactive Nitrogen Species and Disulfide Stress
Sammanfattning : Bacteria have a remarkable ability to adapt to different environments. When bacteria encounter stress that causes macromolecular damage in the cell, leading to a suboptimal performance of cell metabolism, they can elicit an adaptive response. LÄS MER
2. Studies on Redox-proteins and Cytokines in inflammation and Cancer
Sammanfattning : The redox state in the cell plays a major role in determining vital functions and its major imbalance can lead to severe cell injury or death. Redox active proteins and cytokines involved in this process includes thioredoxin (Trx), protein disulfide isomerase (PDI), and tumor necrosis factor (TNF) superfamilies. LÄS MER
3. Proteostasis in Bacillus subtilis : chaperones and stress-response mechanisms
Sammanfattning : The maintenance of protein homeostasis, also referred to as proteostasis, is essential for preserving the structural and functional stability of the proteome in living organisms. This involves the precise control of protein synthesis, folding, and degradation. LÄS MER
4. Thioredoxin and glutaredoxin systems under oxidative and nitrosative stress
Sammanfattning : Our knowledge about reactive oxygen species (ROS) and reactive nitrogen species (RNS) has been changed from simple damaging molecules to redox signaling mediators. ROS/RNS mediated signaling is mainly based on the reversible post-translational modifications of cysteine which works as a switch for protein functions. LÄS MER
5. Roles of intermolecular interactions in amyloid fibril formation mechanisms
Sammanfattning : Amyloid fibrils, a major pathological feature of several neurodegenerative disorders, are highly stable, insoluble aggregates of misfolded proteins. The formation of such aggregates involves a complex equilibrium between protein monomers, different on- and off-pathway transient oligomeric species, and amyloid fibrils. LÄS MER