Sökning: "Granules"

Visar resultat 21 - 25 av 242 avhandlingar innehållade ordet Granules.

1. 21. High-molecular-weight insulin-like growth factor 2 : immunohistochemical, ultrastructural and biochemical findings in insulin cells under normal, diabetic, and neoplastic conditions, and its role in non-islet cell tumour hypoglycaemia

   Författare :Anders Höög; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Insulin-like growth factor-2; IGF-2; islets of Langerhans; B-granules; Diabetes Mellitus type 2; insulinoma; Goto-Kakizaki rat; haemangiopericytoma; ultrastructural immunohistochemistry; gene expression.;

   Sammanfattning : IGF-2 immunoreactive (IR) cells were identified in the normal adult pancreas of man and rat and occurred exclusively in insulin-producing cells. When frozen human pancreatic tissue was extracted and gel-size-separated, a high-molecular-weight (HMW) IGF-2 peptide could be identified. LÄS MER

3. 22. Potato Starch Dispersions: Structure and Rheology

   Författare :Karin Svegmark; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The influence of heating, shearing and addition of amylose on the structure and rheology of potato starch dispersions has been evaluated. The methods used were dynamic viscoelastic measurements, light microscopy and transmission electron microscopy (TEM). LÄS MER

4. 23. Post-transcriptional regulation after stress in Schizosaccharomyces pombe

   Författare :Daniel Nilsson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Post transcriptional regulation;

   Sammanfattning : Post transcriptional regulation is part of the gene expression control and is important for many cellular processes. It influences how mRNAs are selected for translation, degradation or storage. In this thesis, I describe some of the known mechanisms for transcriptional regulation in S. LÄS MER

5. 24. Mechanisms of insulin exocytosis and release

   Författare :Sebastian Barg; Islet cell physiology; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ClC-3; electrophyiology; confocal microscopy; calcium channel; readily releasable pool; exocytosis; insulin; diabetes; green fluorescent protein; Physiology; Fysiologi;

   Sammanfattning : Endocrine cells as well as neurons release their hormones and transmitters by regulated exocytosis. In the pancreatic B-cell, stimuli like glucose initiate biochemical and electrical processes that culminate in influx of Ca2+, which then triggers exocytosis of insulin-containing granules. LÄS MER

7. 25. Molecular mechanisms of biphasic insulin secretion

   Författare :Nikhil R. Gandasi; Sebastian Barg; Christien Merrifield; Uppsala universitet; []
   Nyckelord :Exocytosis; Insulin secretion; Membrane trafficking; Microscopy; Diabetes; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Pancreatic beta-cells secrete insulin in response to increase in blood glucose concentration with a rapid first phase and slower, sustained second phase. This secretion pattern is similar in entire pancreas, isolated islets of Langerhans and single beta-cells and it is disrupted in type 2-diabetes. LÄS MER