Sökning: "Christien Merrifield"

Hittade 1 avhandling innehållade orden Christien Merrifield.

1. 1. Molecular mechanisms of biphasic insulin secretion

   Författare :Nikhil R. Gandasi; Sebastian Barg; Christien Merrifield; Uppsala universitet; []
   Nyckelord :Exocytosis; Insulin secretion; Membrane trafficking; Microscopy; Diabetes; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Pancreatic beta-cells secrete insulin in response to increase in blood glucose concentration with a rapid first phase and slower, sustained second phase. This secretion pattern is similar in entire pancreas, isolated islets of Langerhans and single beta-cells and it is disrupted in type 2-diabetes. LÄS MER