Sökning: "GST"
Visar resultat 1 - 5 av 63 avhandlingar innehållade ordet GST.
1. Insurance in European VAT : On the Current and Preferred Treatment in the Light of the New Zealand and Australian GST Systems
Sammanfattning : Whether and how to tax insurance, one of the crucial elements of the modern economy and society, is a complex issue for the design of laws on value added tax (VAT). Exemption from VAT has been the most common international practice, and it is also applied in the harmonized system of European VAT. LÄS MER
2. Mutational Analysis and Redesign of Alpha-class Glutathione Transferases for Enhanced Azathioprine Activity
Sammanfattning : Glutathione transferase (GST) A2-2 is the human enzyme most efficient in catalyzing azathioprine activation. Structure-function relationships were sought explaining the higher catalytic efficiency compared to other alpha class GSTs. LÄS MER
3. Genetic modification of cholera toxin B subunit for mucosal anti-infectious or anti-pathologic vaccination
Sammanfattning : The development of mucosal vaccines requires antigen delivery systems that can efficiently help to present vaccine antigens to the mucosal immune system. En efficient and well known antigen carrier/delivery system is the B subunit of cholera toxin (CTB). LÄS MER
4. Exploring the steroidogenic activity of glutathione transferases across species
Sammanfattning : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication. However, some GSTs have developed alternative functions. LÄS MER
5. A Novel Route for Construction of Multipurpose Receptors through Chemical Modification of Glutathione Transferases
Sammanfattning : This thesis describes how the human Alpha class glutathione transferase (GST) A1-1 can be reprogrammed either to function as a multipurpose biosensor for detection of small molecule analytes, or as a handle providing for more efficient protein purification.A novel, user-friendly, and efficient method for site-specific introduction of functional groups into the active site of hGST A1-1 is the platform for these achievements. LÄS MER