Sökning: "FK506"

Visar resultat 6 - 10 av 13 avhandlingar innehållade ordet FK506.

  1. 6. Posttransplantational bone disease : the effect of immunosuppressive drugs on bone : clinical and experimental studies

    Författare :Mohamed Mohamed Abdelhadi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Liver transplantation; hyperparathyroidism; bone density; renal transplantation; cyclosporine; prednisolone; tacrolimus; statin; growth plate; rats;

    Sammanfattning : Osteoporosis and pathologic fractures are frequent complications ill patients with end-stage liver or kidney diseases. Although successful transplantation eliminates some factors related to poor organ function, all increased incidence of pathologic fractures was reported ill the early post-transplant period in spite of normalization of the allograft function. LÄS MER

  3. 7. Peptidyl-prolyl cis-trans Isomerases in the Chloroplast Thylakoid Lumen

    Författare :Anna Edvardsson; Alexander Vener; Bertil Andersson; Per Gardeström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidyl-prolyl isomerase activity; Cyclophilin; FKBP; Immunophilin; Chloroplast Thylakoid Lumen; protein characterization; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The Sun is the ultimate energy source on Earth. Photosynthetic organisms are able to catalyze the conversion of solar energy to chemical energy by a reaction called photosynthesis. In plants, this process occurs inside a green organelle called the chloroplast. LÄS MER

  4. 8. Experimental studies on xenograft rejection

    Författare :Guosheng Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The use of animal organs and tissues may provide a solution to the severe and worsening shortage of human grafts. The aims of the present experimental studies were to provide a better understanding of the rejection mechanisms and give new clues for prevention of xenorejection, thereby hopefully contributing to the development of clinical xenotransplantation. LÄS MER

  5. 9. The cell line RN33B transplanted to adult retina

    Författare :Anita Blixt Wojciechowski; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oftalmologi; host glial response; Ophtalmology; differentiation; migration; proliferation; survival; immunosuppression; RN33B; brain-derived precursor cells; retinal degeneration; subretinal transplantation;

    Sammanfattning : The thesis describes the neural precursor cell line RN33B transplanted subretinally to adult healthy and young dystrophic rat retina. The cell line is generated from E12,5 rat raphe nucleus and transduced with the temperature sensitive mutant of the Simian Virus 40 (SV40) large T-antigen. LÄS MER

  7. 10. Neuronal Cell Death and Restoration in the Basal Ganglia: Implications for Huntington's and Parkinson's diseases

    Författare :Oskar Hansson; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; basal ganglia; Parkinson s disease; Huntington s disease; neural transplantation; restoration; NMDA receptor; excitotoxicity; calcium; caspase; neuronal cell death; apoptosis; transgenic mouse; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Huntington's disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia and extensive striatal neuronal death. The mechanism through which the widely expressed mutant huntingtin mediates striatal neurotoxicity is unknown. Excitotoxicity, i.e. LÄS MER