Sökning: "FKBP"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet FKBP.

  1. 1. Molecular dynamics studied by NMR relaxation experiments. Characterization of functional dynamics in the FK506 binding protein FKBP12

    Författare :Ulrika Brath; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nuclear magnetic resonance; NMR; FK506; protein dynamics; chemical exchange; spin relaxation; FKBP12; FKBP; isotope labeling;

    Sammanfattning : The presented thesis work is concerned with the study of molecular dynamics using liquid nuclear magnetic resonance (NMR) spectroscopy. Spin relaxation dispersion experiments in the rotating frame (R1ρ) are employed to provide a detailed, atomic-resolution view of protein dynamics. LÄS MER

  3. 2. Peptidyl-prolyl cis-trans Isomerases in the Chloroplast Thylakoid Lumen

    Författare :Anna Edvardsson; Alexander Vener; Bertil Andersson; Per Gardeström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidyl-prolyl isomerase activity; Cyclophilin; FKBP; Immunophilin; Chloroplast Thylakoid Lumen; protein characterization; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The Sun is the ultimate energy source on Earth. Photosynthetic organisms are able to catalyze the conversion of solar energy to chemical energy by a reaction called photosynthesis. In plants, this process occurs inside a green organelle called the chloroplast. LÄS MER

  4. 3. Identification and characterization of WASP and FKBP-like protein

    Författare :Ing-Marie Viklund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Ulcerative colitis (UC) is a chronic inflammation of the colon which together with the related Crohn s disease (CD) represent the major forms of Inflammatory Bowel Disease (IBD). IBD is believed to arise in a dysfunctional intestinal barrier which allows the normal gut flora to trigger an unwanted chronic immune response in genetically susceptible individuals. LÄS MER

  5. 4. Molecular Profiling and Imaging of Peptides, Proteins and Drugs in Biological Tissue using Mass Spectrometry

    Författare :Anna Nilsson; Per E. Andrén; Garry Corthals; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peptidomics; mass spectrometry; liquid chromatography; MALDI imaging; neuropeptides; drugs; brain; Pharmacology; Farmakologi;

    Sammanfattning : Biological functions within cells and organisms are mainly carried out by the translational products; proteins and peptides. The analysis and characterization of these biomolecules are of great importance for the progress in disease research and biomarker and drug discovery. LÄS MER

  7. 5. Development of Methods for Protein and Peptide Analysis Applied in Neuroscience Utilizing Mass Spectrometry

    Författare :Johan Pierson; Per Andrén; Ulf Bondesson; György Marko-Varga; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Mass spectrometry; Parkinson’s disease; Metabolism; Profiling Mass Spectrometry; Proteomics; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Sammanfattning : This thesis describes the utilization of the matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) and electrospray ionization (ESI) MS techniques for analysis of complex brain tissue samples. Direct molecular profiling of biological samples using MALDI MS is a powerful tool for identifying phenotypic markers. LÄS MER