Sökning: "Cyclophilin"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet Cyclophilin.

  1. 1. Peptidyl-prolyl cis-trans Isomerases in the Chloroplast Thylakoid Lumen

    Författare :Anna Edvardsson; Alexander Vener; Bertil Andersson; Per Gardeström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidyl-prolyl isomerase activity; Cyclophilin; FKBP; Immunophilin; Chloroplast Thylakoid Lumen; protein characterization; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The Sun is the ultimate energy source on Earth. Photosynthetic organisms are able to catalyze the conversion of solar energy to chemical energy by a reaction called photosynthesis. In plants, this process occurs inside a green organelle called the chloroplast. LÄS MER

  3. 2. Apoptotic mechanisms in the neonatal brain following hypoxia-ischemia

    Författare :Ylva Carlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypoxia-ischemia brain caspase-2 cyclophilin D MLK neonatal.;

    Sammanfattning : Neonatal encephalopathy is often perinatally acquired and caused by hypoxia-ischemia (HI). Brain injury develops with a delay, over 12-48 hours, after the insult. Hypothermia, an established neuroprotective treatment, saves 1 infant in 9 from neurological deficits suggesting that there is room for further improvement. LÄS MER

  4. 3. Calcium-induced mitochondrial permeability transition in CNS-derived mitochondria - Pharmacological aspects of specificity and toxicity in neuroprotection

    Författare :Roland Månsson; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; mitochondria; brain; calcium; respiration; cell death; permeability transition; calcium retention; minocycline; neuroprotection; Debio 025;

    Sammanfattning : Mitochondria are the main site for energy conversion in the cell. Under certain circumstances, such as excess calcium retention or production of reactive oxygen species, a pore forms at contact sites between the outer and the normally impermeable inner mitochondrial membrane. LÄS MER

  5. 4. The importance of Cyclophilins and Mps1 in cancer

    Författare :Sonia Simon Serrano; Klinisk neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cyclophilins; liver; fibrosis; HCC; cell cycle; Mps1 and mitosis;

    Sammanfattning : Hepatic fibrosis is a pathological response to chronic liver injuries such as chronic alcohol consumption, non-alcoholic fatty liver disease (NAFLD) or chronic viral infections. No antifibrotic compound has been approved for liver fibrosis and if the cause of the chronic injury is not solved, fibrosis can progress to cirrhosis. LÄS MER

  7. 5. Molecular dynamics studies of water and biomolecules

    Författare :Pekka Mark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis concerns different areas of molecular dynamics (MD) simulations. In the first part of the thesis the ability of liquid water models to mimic the real bulk water properties and the accuracy of the methods to calculate the properties of water from MD simulations were examined. LÄS MER