Visar resultat 1 - 5 av 113 avhandlingar innehållade ordet Oftalmologi.
Sammanfattning : The purpose of the study was to characterise the phenotype with emphasis on electroretinography in four different types of hereditary retinal degeneration and to correlate it to a genotype when possible. Two methods were used: full-field electroretinography for objective assessment of retinal function and mutation screening of blood samples for detection of gene alterations. LÄS MER
Sammanfattning : Retinitis Pigmentosa (RP) is a group of uncured retinal diseases with the world wide incidence of about 1/3500. In spite of the huge efforts in past years, the mechanisms underlying this type of hereditary blindness has not been elucidated and nor any effective treatment available. LÄS MER
Sammanfattning : The thesis describes the neural precursor cell line RN33B transplanted subretinally to adult healthy and young dystrophic rat retina. The cell line is generated from E12,5 rat raphe nucleus and transduced with the temperature sensitive mutant of the Simian Virus 40 (SV40) large T-antigen. LÄS MER
Sammanfattning : Knowledge of the epidemiology of visual impairment in children forms one of the cornerstones in paediatric ophthalmology. To gain an overview of the situation in Sweden an epidemiological study was performed. Totally 2373 visually impaired children were found, giving an age-specific prevalence of 10,9/10 000. Childhood blindness (i. LÄS MER
5. Clinical expressions of juvenile hereditary retinal degenerations and macular dystrophies: Electrophysiological and genetic studies
Sammanfattning : Hereditary retinal degenerations are the most frequent reason for severe visual handicap among young people in Scandinavia today. In the six papers included in this thesis the phenotypic expressions, with emphasis on the electrophysiological findings, of five different juvenile hereditary retinal degenerations are described. LÄS MER