Sökning: "Extracellular matrix"
Visar resultat 41 - 45 av 555 avhandlingar innehållade orden Extracellular matrix.
41. Fatty acids induce potentially atherogenic changes in extracellular matrix proteoglycans
Sammanfattning : Insulin resistance and type 2 diabetes (T2D) are associated with an increased prevalence of atherosclerotic cardiovascular disease (CVD). A key step in the initiation of atherogenesis is retention of low density lipoproteins (LDL) in the intima by chondroitin sulfate (CS)-rich proteoglycans (PG). LÄS MER
42. Functional studies of integrin subunit 1 and its cytoplasmic domain
Sammanfattning : Integrin subunit β1 can form functional heterodimeric receptors together with at least 11different a subunits. These integrins are the main cellular receptors for extracellular matrixproteins such as collagens, fibronectin, laminins, and others, and they are necessary fornormal embryonal development. LÄS MER
43. Immunosuppressive and metastasis-promoting matrisome proteins in pancreatic cancer : the role of galectin 4 and SERPINB5
Sammanfattning : In Sweden 1200-1300 people are diagnosed with pancreatic ductal adenocarcinoma (PDAC) every year. Late diagnosis, together with poor treatment response and resistance to checkpoint inhibitor immunotherapy, contributes to the poor prognosis of the disease. LÄS MER
44. Matrix degrading proteases in vascular disease
Sammanfattning : Diverse processes of vascular disease including lesion growth, plaque rupture and abdominal aortic aneurysm formation are influenced by protease expression. Arteries undergo compensatory remodelling when the mechanical forces that are imposed on them are altered. LÄS MER
45. Interactions of vitronectin and plasminogen with Helicobacter pylori
Sammanfattning : Helicobacter pylori is the main cause of chronic gastritis and peptic ulcer disease in man and is also associated gastric cancer. The spiral shaped H. pylori moves through the gastric mucous layer and colonises the gastric epithelial cells. H. LÄS MER