Sökning: "Extracellular matrix"
Visar resultat 21 - 25 av 555 avhandlingar innehållade orden Extracellular matrix.
21. Complex Formation in the Extra Cellular Matrix- Structural Study of CTLD of Agrrecan, Tenascin-R and Chondroadherin
Sammanfattning : The cells of higher organisms exist in a complex protein network, the extracellular matrix (ECM), which has a wide variety of different components such as glycoproteins, proteoglycans and carbohydrates. As well as being the physical scaffold on which the cells are dependent for their positioning and mobility, the ECM exercises control over the cells, and changes in the matrix will affect the adhesion, proliferation and differentiation properties of these cells. LÄS MER
22. The role of 1-intergrins in skeletal muscle differentiation and extracellular matrix assembly
Sammanfattning : Integrin subunit β1 forms heterodimeric receptors with at least 12 different α-subunits.These integrins are the main cellular receptors for extracellular matrix and they arenecessary for normal development. In this thesis, the effects of lack of integrin subunitβ1 on matrix deposition and on skeletal muscle development were studied. LÄS MER
23. Proteoglycan Lectin Domain Interactions in Extracellular Matrix Assembly
Sammanfattning : This thesis focuses on the C-terminal G3 region of the large aggregating proteoglycans that are found in complex with hyaluronan in the extracellular matrix. The G3 region contains a C-type lectin domain that binds different extracellular matrix proteins playing an integral role in tissue organization during development and remodeling. LÄS MER
24. Extracellular matrix as a regulator of cell behavior : Biological effects of hyaluronan biosynthesis and catabolism
Sammanfattning : Extracellular matrix surrounding cells is an important regulator of cellular functions. Hyaluronan (HA) is a glycosaminoglyean and a constituent component of the extracellular matrix in all tissues. It is synthesized by hyaluronan syntheses (HAS) at the inner surface of cell membrane and degraded by hyaluronidases to small fragments. LÄS MER
25. Basement membrane components in the chondrocyte extracellular matrix
Sammanfattning : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. LÄS MER