Sökning: "Cardiopulmonary bypass"

Visar resultat 1 - 5 av 58 avhandlingar innehållade orden Cardiopulmonary bypass.

  1. 1. Heparin coating and cardiotomy suction in cardiopulmonary bypass

    Författare :Staffan Svenmarker; Torkel Åberg; Gunnar Engström; Thomas Karlsson; Jarle Vaage; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; cardiopulmonary bypass; oxygenators; heparin; S100 proteins; blood loss; haemostasis; memory; outcome and process assessment; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

    Sammanfattning : The present thesis addresses various means of reducing inflammatory responses associated with cardiopulmonary bypass (CPB) and retransfusion of pericardial suction blood (PSB) during cardiac surgery. Four (I-IV) prospective randomised controlled clinical trials comprising 475 patients were performed in the following areas: effects of heparin coating on measures of clinical outcome and memory function (I, II), inflammatory reactions in PSB and its systemic effects after retransfusion using cardiotomy suction or cell salvage (III) and effects of retransfusion of PSB on memory function and release patterns of protein S100B (IV). LÄS MER

  2. 2. Cerebral Perfusion during Cardiopulmonary Bypass

    Författare :Thomas Tovedal; Fredrik Lennmyr; Stefan Thelin; Uppsala universitet; []

    Sammanfattning : Impaired superior vena cava (SVC) cannula outflow during cardiopulmonary bypass (CPB) is a frequent issue, often manifested by only marginal changes in routine monitoring parameters. Nevertheless, significant impact on cerebral perfusion may result. LÄS MER

  3. 3. Cardiopulmonary bypass and the kidney - studies on patients undergoing cardiac surgery

    Författare :Lukas Lannemyr; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiac surgery; cardiopulmonary bypass; glomerular filtration rate; renal blood flow; renal oxygenation; tubular injury; N-acetyl-ß-D-glucoseaminidase;

    Sammanfattning : Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), and has a major impact on morbidity, mortality and costs. The mechanism of CPB-related renal impairment is not fully understood. LÄS MER

  4. 4. Atelectasis and gas exchange impairment after cardiopulmonary bypass : An experimental study

    Författare :Lennart Magnusson; Uppsala universitet; []
    Nyckelord :Medical sciences; Lung: cardiopulmonary bypass; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Physiology; klinisk fysiologi;

    Sammanfattning : Despite of the improvement in management and equipment for cardiopulmonary bypass (CPB), postoperative pulmonary complications remain a major problem after cardiac surgery. In the present thesis, using a pig model, atelectasis has been tested as a cause of the increase in intrapulmonary shunt commonly seen after CPB. LÄS MER

  5. 5. Systemic inflammatory activation during cardiac Surgery. Influence of cardiopulmonary bypass management and patient factors

    Författare :Martin Westerberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :cardiopulmonary bypass; inflammatory response; coagulation; CABG; cardiotomy suction; cytokines;

    Sammanfattning : Cardiac surgery with cardiopulmonary bypass is accompanied by a prominent systemic inflammatory and hemostatic activation, which may contribute to postoperative complications. Aims: To investigate if selection of cardiopulmonary bypass (CPB) system and management of cardiotomy suction (CTS) and mediastinal shed blood (MSB) affect systemic inflammatory response. LÄS MER