Sökning: "CMV"

Visar resultat 26 - 30 av 94 avhandlingar innehållade ordet CMV.

  1. 26. Cytomegalovirus and herpes simplex virus infections in the fetus and newborn infant, with regard to neurodevelopmental disabilities

    Författare :Mona-Lisa Engman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The congenital cytomegalovirus infection (CMV) is the most common congenital infection causing childhood morbidity. The majority (85%) of infected infants have no signs of infection in the newborn period, and when sequelae such as a hearing deficit or neurological impairment manifest themselves, the possibility of a CMV infection is easily overlooked. LÄS MER

  2. 27. Environmental and lifestyle factors, including viral infections, in relation to development of allergy among children in Saint-Petersburg and Stockholm

    Författare :Anna Sidorchuk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Allergic diseases; children; Cytomegalovirus; environmental tobacco smoke; Epstein-Barr virus; farm-related exposure; sensitization; wood smoke;

    Sammanfattning : The increasing prevalence of allergic diseases in children, particularly noteworthy in developed countries, has become an object of international concern. A lack of exposure to a broad range of infectious agents in early life has been suggested as one of the contributing factors. LÄS MER

  3. 28. Insights into biotic stress response in Arabidopsis thaliana : the roles of epigenetics and RNA silencing

    Författare :María Luz Annacondia López; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Plants live in fluctuating environments that can lead to stressful conditions that threat their survival. To deal with these disturbances, plants have developed a fascinating genome plasticity that enables them to reprogram their gene expression and adapt to the new conditions. LÄS MER

  4. 29. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells

    Författare :Björn Carlsson; Magnus Essand; Thomas Tötterman; Malcolm Brenner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunotherapy; Adoptive T cell therapy; Dendritic cell; T cell; Tetramer; Cytomegalovirus; Transplantation; pp65; Prostate cancer; TARP; Prostate antigens; Immunologi; Immunology; Immunologi;

    Sammanfattning : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. LÄS MER

  5. 30. Generation of Therapeutic T Cells for Prostate Cancer

    Författare :Ole Forsberg; Magnus Essand; Thomas Tötterman; Gustav Gaudernack; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; T cells; dendritic cells; peptides; cytomegalovirus; adenovirus; immunotherapy; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : The work presented herein focuses on the activation of the adaptive immune system in order to develop T cell-based immunotherapy for viral infections and cancer. The main goal was to identify and activate viral or tumoral antigen-specific T cells by using different identification, isolation and stimulation techniques. LÄS MER