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Visar resultat 1 - 5 av 94 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Opportunistic viral infection after paediatric transplantation

   Författare :Carola Kullberg-Lindh; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Paediatric liver transplantation; paediatric stem cell transplantation; immunosuppression; opportunistic; CMV; EBV; AdV; HHV-6; real-time PCR; monitoring; specimen; post transplant lymphoproliferative disease;

   Sammanfattning : Background: Opportunistic viral infections can cause considerable morbidity and mortality in organ and stem cell transplanted (SCT) patients, mainly due to iatrogenic T cell dysfunction. Whereas in SCT patients, in general the immunosuppressive treatment can be discontinued after 6-12 months, for the majority of organ transplanted patients, the need for treatment is life-long. LÄS MER

3. 2. Herpesvirus Infection and Immunity in Neurocognitive Disorders

   Författare :Gabriel Westman; Britt-Marie Eriksson; Martin Ingelsson; Olle Korsgren; Jan Ernerudh; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Herpes simplex encephalitis; Herpesvirus; Cytomegalovirus; CMV; HSV-1; HHV-6; CD8 T-cells; Cellular immunity; Immunosenescence; Autoimmunity; NMDA receptor; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Herpesviruses have co-speciated with several vertebrate and invertebrate animals throughout the history of evolution. In the immunocompetent human host, primary infection is usually benign, whereafter the virus is brought into life-long latency. LÄS MER

4. 3. Cellular Immune Responses to Allografts and Cytomegalovirus

   Författare :Mats Engstrand; Olle Korsgren; Gunnar Tufveson; Nils Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Transplantation; Rejection; Monitoring; Flow Cytometry; MHC; Tetramer; CMV; infection; Immunologi; Immunology; Immunologi;

   Sammanfattning : Today the immunosuppressive treatment is kept to a level were the incidence of acute rejection is below 20% within the first year after transplantation. As a consequence, a group of transplanted patients is over-immunosuppressed and at risk for infections. LÄS MER

5. 4. Herpesvirus-induced expression of sLe(x) and related O-linked glycans in the infected cell

   Författare :Kristina Nyström; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HSV-1; CMV; VZV; O-linked glycans; Lewis antigens; ICP0;

   Sammanfattning : Lewis antigens constitute a family of fucosylated carbohydrate antigens (glycotopes), involved in leukocyte homing and related immunological phenomena. These glycotopes are only expressed restrictedly in normal cells, but are induced at appropriate occasions. It is well established that many tumors ?hijack? Lewis glycotopes for e.g. LÄS MER

7. 5. The Immune System in the Oldest-Old : Clinical and Immunological Studies in the NONA Immune Cohort

   Författare :Bengt-Olof Nilsson; Jan Ernerudh; Anders Wikby; Sture Löfgren; Karlis Pauksens; Linköpings universitet; []
   Nyckelord :Elderly; selection; health status; lymphocyte subsets; CD8; CMV; cytomegalovirus; immune risk; immune risk phenotype; IRP; T-cells; interleukin 6; IL-6; survival; mortality; antinuclear antibodies; ANA; ageing; immunosenescence; MEDICINE; MEDICIN;

   Sammanfattning : The oldest-old (people aged 80 or older) constituted 5 % of the population in Sweden in 2000, an increase from 1.5 % fifty years earlier. The immune system undergoes dramatic changes at high age, sometimes referred to as “immunosenescence”. LÄS MER