Sökning: "Bleeding disorders"

Visar resultat 1 - 5 av 35 avhandlingar innehållade orden Bleeding disorders.

  1. 1. Genetic Screening in Patients Suspected of Inherited Bleeding Disorders

    Författare :Marcus Fager Ferrari; Malmö Klinisk koagulationsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bleeding; Inherited Bleeding Disorders; Platelet Dysfunction; Thrombocytopenia; Genetic Screening; High-Throughput Sequencing; STX11; STXBP2; UNC13D; FGB; COL1A1; COL3A1; COL5A1; COL5A2; GNE; Sialic Acid; Oseltamivir;

    Sammanfattning : Inherited bleeding disorders constitute a heterogeneous group of genetic diseases, affecting virtually all major components of the hemostatic system. The diagnostics are potentially complex, and a high proportion of patients remain without a conclusive diagnosis following work-up. LÄS MER

  3. 2. Astheno-emotional disorder after aneurysmal subarachnoid hemorrhage. Classification, outcome, and relation to anxiety and depressive disorders

    Författare :Martin Rödholm; Göteborgs universitet; []
    Nyckelord :Astheno-Emotional disorder; cognition disorders; mental fatigue; amnesia; classification; inter-rater reliability; subarachnoid hemorrhage; outcome; anxiety disorders; depressive disorders.;

    Sammanfattning : Background: Psychiatric symptoms such as fatigue, concentration and memory difficulties, anxiety, and depressiveness are frequently reported after aneurysmal subarachnoid hemorrhage (aSAH) and in various other neurological diseases. These symptoms may indicate the presence of organic psychiatric disorders (OPDs), such as the Astheno-Emotional (AE-) disorder, of anxiety or depressive disorders, or both, but psychiatric classification and differentiation between such disorders have seldom been used in follow-up studies of neurological disease. LÄS MER

  4. 3. Bleeding tendency and health-related quality of life in carriers of haemophilia

    Författare :Anna Olsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carriers of haemophilia; Bleeding; SF-36; Thrombin generation; Genotype;

    Sammanfattning : Haemophilia A and B are X-linked disorders caused by impaired synthesis of coagulation factors VIII and IX, respectively. Women who carry the haemophilia trait have about 50 % of normal factor levels. LÄS MER

  5. 4. Platelet transfusions in hematological disorders

    Författare :Cecilia Karlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Platelets are important for clot formation and vascular integrity. Thrombocytopenic patients with hematological disorders are at risk of bleeding and platelet transfusions are important in supportive care and treatment of lite-threatening bleedings. LÄS MER

  7. 5. Haemophilia B - Diagnostic Insights, Genetic Aspects and Clinical Outcomes

    Författare :Kristina Kihlberg; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coagulation factor IX; Haemophilia B; Haemophilia A; F9 variant; Assay discrepancy; Chromogenic assay; One-stage assay; Bleeding disorders; Quality of life; Immune tolerance induction; Non-neutralising antibodies; Inhibitors; Treatment Adherence; Arthropathy;

    Sammanfattning : Haemophilia B (HB) is a rare inherited bleeding disorder caused by the deficiency of coagulation factor IX (FIX). The major clinical issues are bleedings, often targeting the joints, and the development of neutralising antibodies, i.e. inhibitors, to the FIX replacement therapy. LÄS MER