Sökning: "Non-neutralising antibodies"

Hittade 2 avhandlingar innehållade orden Non-neutralising antibodies.

1. 1. Haemophilia B - Diagnostic Insights, Genetic Aspects and Clinical Outcomes

   Författare :Kristina Kihlberg; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coagulation factor IX; Haemophilia B; Haemophilia A; F9 variant; Assay discrepancy; Chromogenic assay; One-stage assay; Bleeding disorders; Quality of life; Immune tolerance induction; Non-neutralising antibodies; Inhibitors; Treatment Adherence; Arthropathy;

   Sammanfattning : Haemophilia B (HB) is a rare inherited bleeding disorder caused by the deficiency of coagulation factor IX (FIX). The major clinical issues are bleedings, often targeting the joints, and the development of neutralising antibodies, i.e. inhibitors, to the FIX replacement therapy. LÄS MER

3. 2. Monoclonal antibodies and cytokines for therapy of patients with advanced colorectal carcinoma : a clinical and immunological study

   Författare :Anna-Lena Hjelm Skog; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Colorectal carcinoma; Monoclonal antibodies; IL-2; IFN-[alpha]; GM-CSF; cytokine antibodies; neopterin; sIL-2R; immune suppression;

   Sammanfattning : There is a great need for developing and improving treatment alternatives in colorectal carcinoma (CRC). The tumour associated antigen (TAA) GA733/CO17-1A is expressed by more than 90% of all CRCs, on the majority of both primary and metastatic CRC cells. LÄS MER