Sökning: "Assay discrepancy"

Hittade 4 avhandlingar innehållade orden Assay discrepancy.

  1. 1. Haemophilia B - Diagnostic Insights, Genetic Aspects and Clinical Outcomes

    Författare :Kristina Kihlberg; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coagulation factor IX; Haemophilia B; Haemophilia A; F9 variant; Assay discrepancy; Chromogenic assay; One-stage assay; Bleeding disorders; Quality of life; Immune tolerance induction; Non-neutralising antibodies; Inhibitors; Treatment Adherence; Arthropathy;

    Sammanfattning : Haemophilia B (HB) is a rare inherited bleeding disorder caused by the deficiency of coagulation factor IX (FIX). The major clinical issues are bleedings, often targeting the joints, and the development of neutralising antibodies, i.e. inhibitors, to the FIX replacement therapy. LÄS MER

  3. 2. The Perfect Storm? Gluten and type 1 diabetes

    Författare :Emma Adlercreutz; Celiaki och diabetes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKG2D; Celiac disease autoimmunity; Gluten; Type 1 diabetes; Perinatal risk;

    Sammanfattning : Aim: The general objective of the present research was to study the association between type 1 diabetes and celiac disease, and the effects of dietary gluten on the risk of developing type 1 diabetes. More specific aims were as follows: to estimate the prevalence of celiac-disease-associated autoantibodies in children with type 1 diabetes; to study the connection between non-HLA genetic risk markers and autoantibodies associated with type 1 diabetes and celiac disease during the first year after diagnosis of type 1 diabetes; to investigate the effect of gluten on the risk of developing type 1 diabetes; to evaluate the impact of perinatal factors on the risk of developing both type 1 diabetes and celiac disease. LÄS MER

  4. 3. Haemophilia A - In pursuit of optimised outcomes via personalised treatment

    Författare :Alexandros Arvanitakis; Malmö Klinisk koagulationsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Haemophilia A (HA) is a hereditary bleeding disorder, characterised by deficiency of coagulation factor VIII (FVIII). Repeated joint bleeds can lead to permanent joint damage. FVIII replacement therapy has a high cost and can reduce but not completely prevent bleeding. LÄS MER

  5. 4. Brucella in Tajikistan : zoonotic risks of urbanized livestock in a low-income country

    Författare :Elisabeth Lindahl Rajala; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : One of the most powerful megatrends of our time is urbanization. Urban and peri-urban (UPU) farming is a common practice in many low-income countries because it increases the incomes of families that are often restrained by limited economic resources. LÄS MER