Sökning: "Malmö Klinisk koagulationsmedicin"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Malmö Klinisk koagulationsmedicin.
1. Register-based studies to assess long-term outcome in haemophilia
Sammanfattning : IntroductionHaemophilia is a X-linked bleeding disorder affecting mostly males. Women are mainly carriers ofhaemophilia, however, they can expereince high bleeding tendency and assocaited symptoms aswith males. In the absence of the appropriate treatment, bleedings, especially into the joints, result inadverse outcomes. LÄS MER
2. Co-morbidity and mortality in Swedish patients with haemophilia - A register study
Sammanfattning : Haemophilia is an X-linked inherited recessive disorder affecting males. The increased risk of hemorrhage is explained by the deficiency in either coagulation factor VIII (haemophilia A) or IX (haemophilia B). The severity of haemophilia A and B is characterized by the bleeding pattern. LÄS MER
3. Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis
Sammanfattning : The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. LÄS MER
4. Pharmacokinetic dosing of factor VIII and factor IX in prophylactic treatment of haemophilia
Sammanfattning : The aim of the thesis was to increase cost-effectiveness in prophylactic treatment of haemophilia. Prophylaxis is effective to prevent bleedings and arthropathy, but the high cost limits its use. First, a new distribution system for clotting factor concentrates was implemented in Sweden to improve availability and reduce risks and costs. LÄS MER
5. Resistance to activated protein C a novel risk factor for venous thrombosis
Sammanfattning : Activated protein C resistance (APC resistance) is the most common hereditary condition associated with venous thrombosis. The syndrome known as APC resistance is perfectly linked to a mutation in the gene coding coagulation FV (FV:Q506) mutation changing Arg 506 to Gln in the APC cleavage site. LÄS MER