Sökning: "Biology with specialization in Molecular Cell Biology"
Visar resultat 11 - 15 av 101 avhandlingar innehållade orden Biology with specialization in Molecular Cell Biology.
11. Comparative genomics of the genus Mycobacterium : Genome evolution, phylogeny and diversity
Sammanfattning : The genus Mycobacterium includes more than 190 species, and many cause severe diseases such as tuberculosis and leprosy. According to the "World Health Organization", in year 2019 alone, 10 million people developed TB, and 1.4 million died. LÄS MER
12. Cellular and molecular roles for CDC42 in angiogenesis
Sammanfattning : Angiogenesis is the physiological process by which new blood vessels grow and critically depends on the interplay between the major vascular units: endothelial cells, pericytes and smooth muscle cells. Dysfunction and mispatterning of blood vessels are associated with the progression of many vascular complications, and therefore, understanding the causes of vascular dysmorphia is a central question in vascular biology. LÄS MER
13. Colorectal cancer and radiation response : The role of EGFR, AKT and cancer stem cell markers
Sammanfattning : The primary treatment for colorectal cancer is surgery. Radiotherapy and chemotherapy, sometimes combined, are also frequently used to diminish recurrence risk. In response to radiation exposure, several cellular signaling cascades are activated to repair DNA breaks, prevent apoptosis and to keep the cells proliferating. LÄS MER
14. Diversification of TGF-β Signaling in Homeostasis and Disease
Sammanfattning : With the dawn of metazoans, the ability of cells to communicate with each other became of paramount importance in maintaining tissue homeostasis. The transforming growth factor β (TGF-β) signaling pathway, which plays important roles during embryogenesis and in the adult organism, signals via a heterodimeric receptor complex consisting of two type II and two type I receptors. LÄS MER
15. New Molecular Approaches to Glioblastoma Therapy
Sammanfattning : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. LÄS MER
