Sökning: "in vivo infection"

Visar resultat 1 - 5 av 381 avhandlingar innehållade orden in vivo infection.

  1. 1. The Role of Chlamydia pneumoniae-induced Platelet Activation in Cardiovascular Disease : In vitro and In vivo studies

    Författare :Hanna Kälvegren; Torbjörn Bengtsson; Arina Richter; Erik Kihlström; Kenneth Persson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia pneumoniae; Platelet; atherosclerosis; Infection; LDL-oxidation; Percutaneous coronary intervention; Cardiovascular disease; Serotonin; Reactive oxygen species production; Pharmacology; Farmakologi;

    Sammanfattning : The common risk factors for atherosclerosis, such as obesity, high cholesterol levels, sedentary lifestyle, diabetes and high alcohol intake, only explain approximately 50% of cardiovascular disease events. It is thereby important to identify new mechanisms that can stimulate the process of atherosclerosis. LÄS MER

  3. 2. Multiple functions of YopN in the Yersinia pseudotuberculosis type III secretion system : from regulation to in vivo infection

    Författare :Sarp Bamyaci; Åke Forsberg; Edouard Galyov; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system; Yersinia; YopN; virulence; phagocytosis; mouse infection; secretion kinetics;

    Sammanfattning : The type 3 secretion systems (T3SSs) are virulence mechanisms used by various Gram-negative bacteria to overcome the host immunity. They are often target-cell contact induced and activated. Activation results in targeting of virulence effector substrates into host cells. LÄS MER

  4. 3. Twin-arginine translocation in Yersinia : the substrates and their role in virulence

    Författare :Ummehan Avican; Åke Forsberg; Åsa Sjöling; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Yersinia pseudotuberculosis; Tat; virulence; Tat substrates; SufI; stress response; metabolism; infection; transcriptome analysis; Infectious Diseases; infektionssjukdomar; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Pathogenic Yersinia cause a manifold of diseases in humans ranging from mild gastroenteritis (Y. pseudotuberculosis and Y. enterocolitica) to pneumonic and bubonic plague (Y. LÄS MER

  5. 4. Cytokines and Neutrophils in the Urinary Tract Mucosa

    Författare :Long Hang; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; neutrophils; chemokines; urinary tract infection; mucosa; epithelial cells; serology; transplantation; Immunologi; serologi;

    Sammanfattning : This study investigated the urinary tract cytokine reponse to infection and the role of chemokines for neutrophil recruitment to the urinary tract. The results suggest that 1) IL-8 and TGFb are consitutively produced by uroepithelial cells in vivo, and that uroepithelial cells are stimulated to produce IL-1b and IL-6 by uropathogenic Escherichia coli. LÄS MER

  7. 5. Multi-level characterization of host and pathogen in Helicobacter pylori-associated gastric carcinogenesis

    Författare :Kaisa Thorell; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastroenterology; cancer; infection; Helicobacter pylori; sequencing; genomics; transcriptomics; genomics;

    Sammanfattning : Today, more than half of the world’s population is infected with Helicobacter pylori, and two to three per cent of these will develop gastric cancer associated with this infection. Gastric cancer is today the third largest cause of cancer mortality worldwide, with more than 700 000 deaths annually, a number that is expected to increase. H. LÄS MER