Sökning: "cytokine profiling"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden cytokine profiling.

  1. 1. Biogenesis, function and regulation of the type III secretion translocon of Yersinia pseudotuberculosis

    Författare :Salah I. Farag; Matthew S Francis; Jörgen Johansson; Åke Forsberg; Luís Jaime Mota; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; type III secretion system; translocation; translocon; regulation; bacteria-eukaryotic cell contact; cytokine profiling;

    Sammanfattning : Many Gram negative bacteria use type III secretion systems to cross-talk with eukaryotic cells. Type III secretion system assembly and function is tightly regulated. LÄS MER

  3. 2. Proteomic profiling of osteoarthritis. A computational approach to biomarker discovery

    Författare :Martin Rydén; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Computational Biology; Bioinformatics for Proteomics;

    Sammanfattning : Understanding the molecular mechanisms of osteoarthritis (OA) is critical for early diagnosis and effective treatment. OA is a leading cause of disability and poses an increasing burden on healthcare systems, particularly with an aging global population. LÄS MER

  4. 3. Gene expression profiling in autoimmune diseases : a story of ups and downs

    Författare :Miranda Houtman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoimmune diseases are believed to arise from a combination of genetic and environmental factors that affect normal function of immune cells. In this thesis, we studied the functional role of genetic variants, in peripheral blood cells, that relate to rheumatoid arthritis (RA) and myositis by gene expression profiling. LÄS MER

  5. 4. Expression profiling of human macrophages and atherosclerotic plaques to identify genes and mechanisms that modulate the development of atherosclerosis

    Författare :Daniel Hägg; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Macrophages play an important role in atherosclerosis, a disease that affects large and medium size arteries and causes clinical manifestations such as myocardial infarction or stroke. The aim of this thesis was to identify genes that are important in the development of atherosclerosis. LÄS MER

  7. 5. Biomarkers for Peripartum Depression : Focusing on aspects of the immune system and the metabolome

    Författare :Emma Bränn; Alkistis Skalkidou; Emma Fransson; Fotios Papadopoulos; Inger Sundström Poromaa; Daniel Lindqvist; Uppsala universitet; []
    Nyckelord :Peripartum depression; Immune system; Metabolome; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Peripartum depression is a common, multifactorial, and potentially devastating disease among new mothers. A biological marker for peripartum depression would facilitate early detection, better understanding of the pathophysiology, and identification of targets for treatment. LÄS MER