Sökning: "transcription factor yeast"

Visar resultat 1 - 5 av 61 avhandlingar innehållade orden transcription factor yeast.

1. 1. Imaging of nucleocytoplasmic transcription factor dynamics in yeast

   Författare :Kristofer Bodvard; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transcription factor; single-cell; yeast; image analysis; Saccharomyces cerevisiae; light stress; Fluorescence microscopy; signalling;

   Sammanfattning : Fluorescence microscopy has proven to be an invaluable tool in identifying and understanding cell signalling, intracellular spatial and temporal dynamics, and cell-to-cell variability. This thesis focuses on imaging of nucleocytoplasmic transcription factor dynamics at the single cell level in yeast. LÄS MER

3. 2. Studies of the chromatin form of yeast Mediator and the function of its tail module

   Författare :Miriam Nilsson; Stefan Björklund; Claes Gustafsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mediator complex; Transcriptional regulation; yeast; tail module; transcription; medicinsk biokemi; Medical Biochemistry; molekylärbiologi; Molecular Biology;

   Sammanfattning : Mediator is a large, multifunctional complex that is conserved in eukaryotes. It was first discovered in Saccharomyces cerevisiaeas required for transcriptional activators to function in a reconstituted in vitro system. Mediator is also important for stimulation of basal, unregulated transcription, and transcriptional repression. LÄS MER

4. 3. The acidic domain, the human version and the protein interaction of the ETS transcription factor SPI-C

   Författare :Robert Carlsson; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; B-lymphocyte; phylogeny; STAT6; SPI-C; transcription;

   Sammanfattning : Primary infections and vaccination stimulates the immunesystem to produce memory cells that rapidly respond to reexposure of the same antigen. These memory responses are dependent on an adaptive type of immunity that sustains the reactivity of the immune system by long-lived memory immune cells. LÄS MER

5. 4. Illumination in single cell optical microscopy studies - friend and foe

   Författare :Kristofer Bodvard; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; yeast; transcription factors; signalling; fluorescence microscopy; Saccharomyces cerevisiae; light-induced stress; phototoxicity; single cell imaging;

   Sammanfattning : This thesis focuses on how to use light as a biological stress factor in optical microscopy experiments and simultaneously use the illumination to image the spatial and temporal protein dynamics in single yeast cells. The stress responses to environmental changes other than light have been extensively investigated in budding yeast, Saccharomyces cerevisiae, often using techniques based on population averages. LÄS MER

7. 5. Silencing and DNA double-strand break repair in budding yeast

   Författare :Andreas Kegel; Stefan Åström; Stephan Marcand; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Silencing; Reb1; DSB; NHEJ; Nej1; illegitimate recombination; yeast; Developmental biology; Utvecklingsbiologi;

   Sammanfattning : Transcriptional silencing that makes large chromosomal domains inaccessible for the transcriptional apparatus is nucleated at DNA elements called silencers. In K.lactis a 102bp HMLα silencer was defined revealing three distinct protein-binding regions (A, B, and C) that were required for silencing of HMLα. LÄS MER