Sökning: "the free-energy principle"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden the free-energy principle.
1. Understanding molecular mechanisms of protein tyrosine kinases by molecular dynamics and free energy calculations
Sammanfattning : Background: Insulin receptor kinase (IRK) and Insulin-like growth factor 1 receptor kinase (IGF-1RK) are two important members in the large class of tyrosine kinase receptors. They play pivotalroles in the regulation of glucose homeostasis, cell proliferation, differentiation, motility, andtransformation. LÄS MER
2. From Static Structures to Free Energy Landscapes: Characterizing Conformational Transitions in Biological Macromolecules
Sammanfattning : To be alive means to temporarily counteract the fundamental dispersive driving force described by the second law of thermodynamics, eventually leading all systems to decay and disorder. In cells, this task is partly carried out by proteins - small specialized molecular machines that utilize free energy to maintain the proper functioning of the cell. LÄS MER
3. Reality-based brain-computer interaction
Sammanfattning : Recent developments within human-computer interaction (HCI) and cognitive neuroscience have come together to motivate and enable a framework for HCI with a solid basis in brain function and human reality. Human cognition is increasingly considered to be critically related to the development of human capabilities in the everyday environment (reality). LÄS MER
4. A Continuum Framework for Modeling the Excitation–Contraction Coupling of Smooth Muscle
Sammanfattning : Excitation-contraction coupling of smooth muscle refers to a chain of coupled physiological processes which convert a stimulus to a mechanical response. These processes can be disassociated into ionic transport during cell membrane excitation, activation of myosin light chains, and muscle contraction caused by actin-myosin interaction (filament sliding). LÄS MER
5. Structural, Kinetic and Thermodynamic Aspects of the Crystal Polymorphism of Substituted Monocyclic Aromatic Compounds
Sammanfattning : This work concerns the interrelationship between thermodynamic, kinetic and structural aspects of crystal polymorphism. It is both experimental and theoretical, and limited with respect to compounds to substituted monocyclic aromatics. LÄS MER