Sökning: "steroid hormone receptors"

Visar resultat 6 - 10 av 49 avhandlingar innehållade orden steroid hormone receptors.

  1. 6. Targeted therapeutic strategies for prostate cancer treatment using novel lipid kinase inhibitors in combination with current drugs

    Författare :Julius Semenas; Jenny L. Persson; Anna Berghard; Maria Fällman; Thomas Grundström; Lukas Kenner; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; bone metastasis; castration-resistant; treatment; precision therapy; PIP5K1A; steroid hormone receptors; cancer stem cells; Oncology; onkologi;

    Sammanfattning : Prostate cancer (PCa) is one of the most common cancer types and the fifth cancer-related cause of death among Western world men.  The sex steroid hormone, androgen and androgen receptor (AR) play important roles in PCa progression. LÄS MER

  3. 7. Clinical Aspects of Hereditary Breast Cancer

    Författare :Niklas Loman; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; Cytologi; onkologi; cancerology; oncology; Cytology; Age of onset; Survival analysis; Incidence; Male breast cancer; Steroid receptors; BRCA2; BRCA1; Breast cancer; hereditary;

    Sammanfattning : A positive family history of breast cancer (BC) is one of the strongest predictors of the disease. Two major BC susceptibility genes, BRCA1 and BRCA2 were identified about a decade ago. In this thesis, studies of different biological. clinical and epidemiological aspects of hereditary BC are presented. LÄS MER

  4. 8. Hormonal Regulation of Vaginal Mucosa

    Författare :Theodora Kunovac Kallak; Anneli Staverus-Evers; Inger Sundström Poromaa; Philippa Saunders; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aromatase inhibitors; vaginal atrophy; estrogen; proliferation; steroid hormone receptors; cell differentiation; cell adhesion; aquaporin 3;

    Sammanfattning : Vaginal atrophy symptoms such as dryness, irritation, and itching, are common after menopause. Vaginal estrogen therapy is the most effective treatment but not appropriate for all women. LÄS MER

  5. 9. The relative importance of sex steroid receptors for bone metabolism

    Författare :Sofia Movérare-Skrtic; Göteborgs universitet; []
    Nyckelord :bone; estrogen; androgen; transgenic; microarray;

    Sammanfattning : Estrogen deficiency increases the risk of a wide variety of pathological conditions including osteoporosis. Morbidity from osteoporosis is substantial in both men and women. LÄS MER

  7. 10. Estrogens and the urogenital tract : studies on steroid hormone receptors and a clinical study on a new estradiol-releasing vaginal ring

    Författare :Peter Smith; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER