Sökning: "steroid hormone receptors"

Visar resultat 21 - 25 av 49 avhandlingar innehållade orden steroid hormone receptors.

  1. 21. Hormonal regulation of the primate uterus : effects of hormone treatment and lifestyle intervention

    Författare :Mariana Hulchiy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :endometrium;

    Sammanfattning : The uterus is a major hormone-responsive reproductive organ in primates. Hormones promote their effect via different pathways. Receptors involved in steroid hormone, thyroid hormone and insulin signaling have been found in the endometrium. LÄS MER

  3. 22. Transcriptional regulation by the thyroid hormone receptor and its viral counterpart : the P75gag-V-erbA oncoprotein

    Författare :Gunilla Wahlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Transcriptional regulation; thyroid hormone; TR; P75gag-v-erbA; repression; Avian erythroblastosis virus; response elements; RXR; retinoids.;

    Sammanfattning : Thyroid hormone binds to specific DNA binding receptors (TRs) in the cell nucleus and thus regulates transcription during development and in some pathological disorders. The gene of the viral TR homologue, v-erbA, is one of two oncogenes encoded in the genome of avian erythroblastosis virus (AEV). LÄS MER

  4. 23. Hormones and breast cancer : aspects on receptor expression and metabolism

    Författare :Lars Löfgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast cancer; fine needle aspiration biopsy; tamoxifen; megestrol acetate; SHBG; sex steroid hormone receptors; Syndecan-1;

    Sammanfattning : Breast cancer is the most common malignancy among women in the western world. Sex steroid hormones are implied as risk factors but endocrine regimens are also used in the therapy of breast cancer. Current knowledge about the endocrine and metabolic effects of different treatments is incomplete. LÄS MER

  5. 24. Estrogen receptor gene activity within the brain and the relation to psychiatric disorders : mapping and function

    Författare :Marie Österlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :steroid hormone; ER system; in situ hybridization; rnRNA; ER serotonin; depression; affective disorders;

    Sammanfattning : Estrogens have for a long time been known to regulate neuroendocrine functions in the central nervous system (CNS), primarily related to reproduction. In recent years estrogens have been found to also modulate many other brain functions, for example mood and cognition. LÄS MER

  7. 25. Studies on the extracellular matrix of the dysfunctional pelvic floor

    Författare :Marie Westergren Söderberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pelvic floor; pelvic organ prolapse; stress urinary incontinence; extracellular matrix; collagen; SLRPs; decorin; lumican; fibromodulin; elastin associated proteins; fibrillin-1; fibulin-5; sex steroid hormone receptors; ER; PR; AR;

    Sammanfattning : Objective: Pelvic floor dysfunction cause impaired quality of life of many women and is one of the most common reasons for gynaecological surgery on benign indications. Little is known about the pelvic floor extracellular matrix as a pre-requisite for mechanical sustainability through vaginal delivery, age and hormonal changes. LÄS MER