Sökning: "stem- progenitor cells"

Visar resultat 16 - 20 av 264 avhandlingar innehållade orden stem- progenitor cells.

1. 16. Characterization of Retinal Progenitor Cells : Focus on Proliferation and the GABAA Receptor System

   Författare :Henrik Ring; Finn Hallböök; Per Söderberg; Andras Simon; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regeneration; Proliferation; Neurotransmitters; Müller cells; Differentiation; Retinal repair; Neurogenesis; Medical Science; Medicinsk vetenskap;

   Sammanfattning : One strategy to repair an injured or degenerated retina is to stimulate the replacement of damaged or dead neurons with cells derived from endogenous stem- or progenitor cells. A successful strategy requires knowledge about how the proliferation and differentiation of the endogenous cells are regulated. LÄS MER

3. 17. Transposable Elements in Neural Progenitor Cells

   Författare :Liana Fasching; Molekylär neurogenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable Elements; TRIM28; Epigenetic Regulation; Gene Expression; Neural Progenitor Cells;

   Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER

4. 18. Identification and Characterization of Stem Cells in Preleukemia and Leukemia

   Författare :Lars Nilsson; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; extracellulära vätskor; Hematologi; Philadelphia chromosome; acute lymphoblastic leukemia; polycytemia vera; 5q- syndrome; myelodysplastic syndromes; self-renewal; preleukemia; Hematopoietic stem cells; leukemic stem cells; extracellular fluids;

   Sammanfattning : Hematopoietic stem cells (HSCs) are responsible for the daily and life long production of large numbers of mature blood cells through highly regulated self-renewal and multilineage capabilities. Leukemias on the other hand, are characterized by a clonal, dysregulated, lineage skewed proliferation and impaired differentiation as the result of multiple accumulated genetic events. LÄS MER

5. 19. Stem cells : proliferation, differentiation, migration

   Författare :Anna Falk; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Embryonic stem cell; adult neural stem cells; proliferation; differentiation; migration;

   Sammanfattning : A stem cell is demanding and requires precise conditions to carry out its unique tasks. This includes proliferation as an undifferentiated stem cell, differentiation to more mature cell types, migration through tissue to its final destination, and functional integration into the cellular network. LÄS MER

7. 20. Cellular pathways and molecular regulation of hematopoietic stem cells

   Författare :Kristina Anderson; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-catenin.; lineage commitment; hematopoietic stem cells; lineage priming; Wnt signaling pathway; biphenotypic cells; PAX5;

   Sammanfattning : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. LÄS MER