Sökning: "Transposable Elements"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden Transposable Elements.

  1. 1. Transposable Elements in Neural Progenitor Cells

    Författare :Liana Fasching; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable Elements; TRIM28; Epigenetic Regulation; Gene Expression; Neural Progenitor Cells;

    Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER

  3. 2. Transposable Elements in the Healthy and Diseased Human Brain

    Författare :Raquel Garza; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable elements; Neuroscience; Neuroinflammation; Evolution; Epigenetic regulation; Bioinformatics;

    Sammanfattning : .... LÄS MER

  4. 3. The Epigenetic Impact of Transposable Elements in Human Brain Development

    Författare :Per Ludvik Brattås; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transposable elements; epigenetics; neural stem cells; human brain development; gene regulation; human brain evolution;

    Sammanfattning : .... LÄS MER

  5. 4. Cis-regulatory variation and divergence in Capsella

    Författare :Kim A. Steige; Tanja Slotte; Jeff J. Doyle; Uppsala universitet; []
    Nyckelord :Capsella; Shepherd s Purse; cis-regulatory changes; allele-specific expression; mating system shift; floral evolution; polyploidy; positive selection; purifying selection; transposable elements; small RNA; methylation; transposable element silencing; distribution of fitness effects;

    Sammanfattning : Cis-regulatory changes in e.g. promoters or enhancers that affect the expression of a linked focal gene have long been thought to be important for adaptation. In this thesis, I investigate the selective importance and genomic correlates of cis-regulatory variation and divergence in the genus Capsella, using massively parallel sequencing data. LÄS MER

  7. 5. Drivers of evolutionary change in Podospora anserina

    Författare :Sandra Lorena Ament-Velásquez; Hanna Johannesson; Bengt Olle Bengtsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Podospora; Meiotic drive; Spore killing; vegetative incompatibility; heterokaryon incompatibility; allorecognition; speciation; Transposable elements; selfish genetic elements; fungi; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Genomic diversity is shaped by a myriad of forces acting in different directions. Some genes work in concert with the interests of the organism, often shaped by natural selection, while others follow their own interests. The latter genes are considered “selfish”, behaving either neutrally to the host, or causing it harm. LÄS MER