Sökning: "Andras Simon"

Hittade 2 avhandlingar innehållade orden Andras Simon.

1. 1. The molecular biology of retinoid metabolism : identification of an 11-cis retinol dehydrogenase in the retinal pigment epithelium

   Författare :András Simon; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :11-cis retinol; 11-cis retinol dehydrogenase; chromophore; 11-cis retinaldehyde; 9-cis retinol; 9-cis retinol dehydrogenase; retinal pigment epithelium; vitamin A; short-chain alcohol dehydrogenase;

   Sammanfattning : Vitamin A derivatives (retinoids) are essential molecules in the course of embryonic development, postnatal growth and adult physiology. The physiological functions of retinoids are thought to be mediated mainly by retinoic acid which regulates the expression of various genes, and 11-cis retinaldehyde, which is the common chromophore of visual pigments. LÄS MER

3. 2. Characterization of Retinal Progenitor Cells : Focus on Proliferation and the GABAA Receptor System

   Författare :Henrik Ring; Finn Hallböök; Per Söderberg; Andras Simon; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regeneration; Proliferation; Neurotransmitters; Müller cells; Differentiation; Retinal repair; Neurogenesis; Medical Science; Medicinsk vetenskap;

   Sammanfattning : One strategy to repair an injured or degenerated retina is to stimulate the replacement of damaged or dead neurons with cells derived from endogenous stem- or progenitor cells. A successful strategy requires knowledge about how the proliferation and differentiation of the endogenous cells are regulated. LÄS MER