Sökning: "spinal cord injury"

Visar resultat 26 - 30 av 170 avhandlingar innehållade orden spinal cord injury.

  1. 26. Housing accessibility and participation among older adults with long-standing spinal cord injury

    Författare :Lizette Norin; Aktivt och hälsosamt åldrande; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spinal Cord Injuries; housing accesibility problems;

    Sammanfattning : En stödjande miljö är centralt för att kunna upprätthålla ett självständigt liv och effektivt aktivitetsutförande, särskilt med ökande ålder. För personer med funktionella begränsningar, som konsekvenserna av en ryggmärgsskada, är balansen mellan personens funktionella kapacitet och miljöns krav av yttersta vikt för att kunna leva ett så välfungerande liv som möjligt. LÄS MER

  3. 27. Cardiovascular disease prevention after spinal cord injury : a new challenge

    Författare :Kerstin Wahman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Spinal cord injury; traumatic paraplegia; cardiovascular decease; lifestyle; cardiovascular decease prevention;

    Sammanfattning : Spinal cord injury (SCI) typically leads to permanent infralesional motor and sensory functional losses, pathophysiological aberrations in most organ systems and a lasting vulnerability for a variety of complicating conditions. Improvements in acute and rehabilitative management during the last decades have increased long term survival after SCI. LÄS MER

  4. 28. Trophic factors, neuroprotection and spinal cord repair

    Författare :Johan Widenfalk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :spinal cord injury; GDNF; GFRalpha; neurotrophin; VEGF; olfactory ensheathing glia; weight-drop injury; in situ hybridization;

    Sammanfattning : Background: There is no cure for paralysis. The only drug therapy presently in use, acute high-dose methylprednisolone, has only modest effects on outcome. There is therefore a great need for new therapies. LÄS MER

  5. 29. Medical problems associated with spinal cord lesions - impact on functioning

    Författare :Kirsi Valtonen; Göteborgs universitet; []
    Nyckelord :spinal cord injuries; meningomyelocele; rehabilitation; osteoporosis; bone density; employment; sexuality;

    Sammanfattning : Aims: The overall aim of this thesis was to study the effects of medical problems associated with spinal cord lesions on functioning - with special interest in work participation and sexual functioning. A special aim was to explore bone mineral density and associated factors in persons with meningomyelocele. LÄS MER

  7. 30. PACAP and orphanin FQ/nociceptin -Distribution, importance and regulation in sensory neurons and spinal cord

    Författare :Lina Pettersson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; neuropsychology; Neurology; trk; spinal cord; sensory neuron; rat; PAC1; PACAP; ORL1; OFQ N; neurotrophin; neuropeptide; nerve transection; nerve compression; inflammatory pain; BDNF; DRG;

    Sammanfattning : Neuropeptide expression in the nervous system is abundant and plastic, and an altered expression after injury is an example of a functional response, helping the neuron to cope with adverse changes, and involves effects on differentiation, synthesis, repair/regeneration, survival, and modulation of signal transmission. I have investigated the distribution/expression of the neuropeptides, orphanin FQ/nociceptin (OFQ/N) and pituitary adenylate cyclase activating polypeptide (PACAP), under normal conditions, in response to nerve injuries, and also studied sensory responses in mice deficient for the PAC1 receptor (PAC1-/-). LÄS MER