Sökning: "smooth muscle differentiation"
Visar resultat 21 - 25 av 53 avhandlingar innehållade orden smooth muscle differentiation.
21. Functional Proteome analysis of the molecular mechanism of (myo)fibroblast differentiation
Sammanfattning : Tissue remodeling is observed in several physiological conditions such as embryogenesis, senescence, wound healing and pregnancy, as well as in several pathological conditions such as fibrosis and tumorgenesis. Fibroblasts play a key role in this tissue remodeling due to their capability of altering the turnover of the extracellular matrix. LÄS MER
22. Mechanisms involved in the regulation of secretory phospholipase A2 Type IIA expression in human arterial smooth muscle cells. Potential role in atherogenesis
Sammanfattning : Experimental and clinical evidence indicates that secretory phospholipase A2 group IIA (sPLA2-IIA) contributes to atherogenesis. Activity of sPLA2-IIA may be pro-atherogenic both in the circulation leading to altered lipoprotein profile and/or locally in the artery wall where it contributes to lipid accumulation both intra and extra cellularly. LÄS MER
23. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo
Sammanfattning : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. LÄS MER
24. Retinoids in the modulation of vascular inflammation
Sammanfattning : Vascular disease is multifactorial. Smooth muscle cells, the major constituent of the normal vessel wall, play a pivotal role. The pathogenesis includes cellular differentiation, proliferation and inflammatory activation. LÄS MER
25. Opioid ligands and receptors of the joint
Sammanfattning : The aim was to explore the occurrence of an opioid system in joints. Thus, joint tissues from rats with and without arthritis and also from patients with knee osteoarthrosis were investigated by EM, immunohistochemistry, RIA, HPLC, receptor binding assay and RT-PCR. LÄS MER