Sökning: "restenosis"

Visar resultat 1 - 5 av 41 avhandlingar innehållade ordet restenosis.

  1. 1. Clinical And Experimental Studies of Contact Allergy to Stent Metals - with focus on gold

    Författare :Susanne Ekqvist; Yrkes- och miljödermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B-Au; patch testing; restenosis; contact allergy; Dermatology; metals; gold; stent; B-Ni; nickel;

    Sammanfattning : A large number of patients are treated with coronary stents, and restenosis (recurrent narrowing of the vessel) is a serious problem. Contact allergy to metal ions eluted from stainless steel stents has been suggested to contribute to in-stent restenosis. LÄS MER

  3. 2. Experimental studies on thrombin inhibition in acute- and chronic models of vessel wall injury

    Författare :Fredrik Scherstén; Göteborgs universitet; []
    Nyckelord :animal model; antithrombin; fibrinogen; histomorphology; melagatran; percutaneous coronary intervention; platelets; restenosis; stent; thrombin inhibition; thrombosis;

    Sammanfattning : Background: The number of percutaneous coronary interventions (PCI) performed worldwide has increased dramatically during the last decade. Complication rates have decreased over time, however the restenosis phenomenon remains an unsolved issue. Thrombin is the key regulator in the pro-coagulant state following PCI. LÄS MER

  4. 3. Fibromodulin and Dystrophin in Atherosclerosis: Novel roles for extracellular matrix in plaque development

    Författare :Annelie Shami; Kärlväggsbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; fibromodulin; dystrophin; carotid artery; lipid accumulation; restenosis; plaque;

    Sammanfattning : Cardiovascular disease represents nearly half the cases of noncommunicable diseases worldwide and is the leading global cause of death. The main underlying cause is atherosclerosis, and in atherosclerotic plaque progression the structure, composition and integrity of a dynamic extracellular matrix (ECM) is one very important factor. LÄS MER

  5. 4. Mechanisms of thrombosis and restenosis after vascular injury

    Författare :Carl Magnus Wahlgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Restenosis; neointimal hyperplasia; thrombin inhibition; angioplasty; PTA; outcome analysis; coagulation; inflammation; CRP; thioredoxin; oxidative stres;

    Sammanfattning : Atherosclerosis is the underlying cause of about 50% of all deaths in the western world. Peripheral vascular disease commonly affects the arteries supplying the leg and is mostly caused by atherosclerosis. LÄS MER

  7. 5. Signal transduction in restenosis and myocardial protection by hyperoxia

    Författare :Arno Ruusalepp; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neointima; inflammation; NF-kappaB; preconditioning; MAPK; nitric oxide;

    Sammanfattning : Ischemic heart disease is a major cause of morbidity and mortality in the western world. Revascularization of ischemic myocardium is essential for cell survival, and is performed by thrombolysis, percutaneous transluminal coronary angioplasty (PTCA) and by coronary artery bypass grafting. LÄS MER