Avancerad sökning

Visar resultat 1 - 5 av 15 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Digital Twins : High Resolution Disease Models for Optimized Diagnosis and Treatment

    Författare :Sandra Lilja; Mikael Benson; Huan Zhang; Claudio Altafini; Yvan Saeys; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : To study immune-mediated diseases, which can affect the expression of thousands of genes among many different cell types and organs, is a daunting challenge. However, for effective diagnosis and therapeutic treatment it is relevant to understand the regulatory functions of disease. LÄS MER

  3. 2. Leukocyte sequestration associated with inflammation : mechanisms and modulations

    Författare :Kristina Nyhlén; Åke Ryrfeldt; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Inflammationsreaktionen är kroppens första försvar mot främmande partiklar t ex bakterier. Det är en komplex reaktion som bl a karakteriseras av att vita blodkroppar dras till det inflammerade området och att vätskao i blodet lättare tar sig igenom kärlväggen till vävnaden dvs det svullnar. LÄS MER

  4. 3. Studies on the function of CD4CD25 regulatory T cells: An in vitro approach

    Författare :Lukas Cederbom; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; CD152; Costimulation; Dendritic cells; Regulatory T cells; CD4 CD25 ; serology; transplantation; Immunologi; serologi;

    Sammanfattning : Immunological self-tolerance is a state of the whole organism where deleterious responses are either avoided or regulated. Breaking of immunological tolerance will lead to autoimmune disease or chronic inflammatory conditions. LÄS MER

  5. 4. Model Systems for Metal - DNA Interactions. With a Focus on Anticancer Active Platinum(II) Complexes

    Författare :Anna Ericson; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; kinetics; DNA; poly d T ; guanine; 6-thioinosine-5 -monophosphate; 6-thio-2 -deoxyinosine; 4-thiouridine-5 -monophosphate; 4-thio-2 -deoxyuridine; palladium II ; Gold III ; platinum II ; mechanism; salt effect; activation parameters; Inorganic chemistry; Oorganisk kemi;

    Sammanfattning : Reactions of trans-dicyanodichloroaurate(III) trans-dibromodicyanoaurate(III), trans-diamminedichlorogold(III), cis-diammine(aqua)chloroplatinum(II), cis-ammineaqua-(cyclohexylamine)chloroplatinum(II), chloro(terpyridine)platinum(II) and chloro-(diethylenetriaminepalldium(II) with dimethyl sulfide, thionucleosides, thionucleotides and thione- and guanine-containing 17-mer oligonucleotides have been investigated by use of conventional and high-pressure stopped-flow spectrophotometry and HPLC technique as a function of ionic strength, pH, temperature and pressure in aqueous solutions. The mechanism and rate of oxidation of dimethyl sulfide by gold(III) complexes depends on the concentration of free halide. LÄS MER

  7. 5. Identification of Arthritis Regulating Genes in Rats

    Författare :Peter Olofsson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; transplantation; Clinical genetics; Klinisk genetik; serology; Immunology; QTL; RA; Epistasis; Ncf1; Linkage; PIA; Arthritis; Rat;

    Sammanfattning : The immune response is designed to protect the body from harmful microbial invasions. However, when the immune system attacks itself instead, an autoimmune reaction starts that damage our own cells, tissues and organs. LÄS MER