Sökning: "recognition receptors"
Visar resultat 1 - 5 av 185 avhandlingar innehållade orden recognition receptors.
1. Peptidoglycan Recognition Proteins : Major Regulators of Drosophila Immunity
Sammanfattning : All eukaryotic organisms have an innate immune system characterized by germ-line encoded receptors and effector molecules, which mediate detection and clearance of microbes such as bacteria, fungi, and parasites. VertebrateDrosophila as a genetically tractable organism with a This thesis concerns the peptidoglycan recognition protein (PGRP) gene family in the fruit fly. LÄS MER
2. Pattern-recognition receptors in airway inflammation
Sammanfattning : Airway inflammation is a defining feature of allergic rhinitis and asthma. Bacterial and viral infections are known to cause exacerbations of both diseases, but knowledge about the mechanisms involved is limited. LÄS MER
3. TRÖGER´S BASE AS SCAFFOLD FOR SYNTHETIC RECEPTORS
Sammanfattning : This work focuses on the use of the Tröger´s base as organic scaffold for the construction of synthetic receptors for different classes of organic molecules. The structural properties of the Tröger's base, i.e. chirality, rigidity and curvature, allow for synthetic modifications towards the recognition of different molecules. LÄS MER
4. Synthesis and binding studies of 9,10-disubstituted anthracene and dibenzobarrelene-based receptors for recognition of carbohydrates in water
Sammanfattning : Artificial, amfiphilic, and biomimetic receptors soluble in water were synthesized via attaching polar amino acids to hydrophobic back-bones possessing a surface suitable for hydrophobic interactions. The hydrophobic back-bones chosen in this thesis were anthracene and dibenzobarrelene structures. LÄS MER
5. QCM-based sensing using biological and biomimetic interfaces
Sammanfattning : The objective of this thesis was to explore novel approaches for studying molecular recognition at biological and biomimetic surfaces using the quartz crystal microbalance (QCM) biosensor technique. The first two papers focused on the synthesis and study of biotin selective polymer films prepared using the molecularly imprinted polymer (MIP) technique. LÄS MER