Sökning: "peptidoglycan recognition protein"
Visar resultat 1 - 5 av 10 avhandlingar innehållade orden peptidoglycan recognition protein.
1. Peptidoglycan Recognition Proteins : Major Regulators of Drosophila Immunity
Sammanfattning : All eukaryotic organisms have an innate immune system characterized by germ-line encoded receptors and effector molecules, which mediate detection and clearance of microbes such as bacteria, fungi, and parasites. VertebrateDrosophila as a genetically tractable organism with a This thesis concerns the peptidoglycan recognition protein (PGRP) gene family in the fruit fly. LÄS MER
2. Peptidoglycan recognition proteins in Drosophila melanogaster
Sammanfattning : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). LÄS MER
3. Innate Immune Proteins in a Crustacean Pacifastacus leniusculus
Sammanfattning : Hemocytes (blood cells) are important in the immune defense against pathogens in invertebrates. In crusteacean, the hemocytes and plasma components mount a strong innate immune response against different pathogens including bacteria and virus. LÄS MER
4. Vesicle-mediated and free soluble delivery of bacterial effector proteins by oral and systemic pathogens
Sammanfattning : Periodontitis, the primary cause of tooth-loss worldwide, is a bacterially induced chronic inflammatory disease of the periodontium. It is associated with systemic conditions such as cardiovascular disease (CVD). However, pathogenic mechanisms of periodontitis-associated bacteria that may contribute to the CVD association are unclear. LÄS MER
5. Identification and characterisation of five innate immune genes in the cabbage looper Trichoplusia ni
Sammanfattning : When insects are infected with bacteria, they respond by producing a range of different antibacterial peptides and by activating protease cascades leading to coagulation and melanisation. Cellular defence mechanisms are also involved in killing of microorganisms through phagocytosis and encapsulation. LÄS MER