Sökning: "rearrangements"

Visar resultat 26 - 30 av 237 avhandlingar innehållade ordet rearrangements.

  1. 26. Rearrangements to vinyl substituted hetero- and carbocycles : Total synthesis of siphonazole B and otherapplications in oxazole and saturated ringsynthesis

    Författare :Filip Paulsen; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The aim of this thesis is to explore and develop new reactions for rapid generation of molecular complexity. Byenabling access to important molecules in a less wasteful and more cost-efficient manner such developmentbenefits the whole modern society, where increasingly complex molecules are needed to solve problems withinfields ranging from medicine, to materials sciences and the perfume industry. LÄS MER

  3. 27. Prognostic factors in squamous cell carcinoma of the head and neck, with emphasis on 11q13 rearrangements and cyclin D1 overexpression

    Författare :Jan Åkervall; Lund näs- och halssjukdomar Öron-; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; audiologi; Otorinolaryngologi; auditive system and speech; audiology; head and neck; squamous cell carcinoma; genetics; prognosis; CCND1; chromosomes; cyclin D1; chemotherapy; Otorhinolaryngology; gene expression; hörsel- och talorganen;

    Sammanfattning : At present, clinical outcome or response to therapy can not be fully predicted in individual cases of squamous cell carcinoma of the head and neck (SCCHN). The overall aim of the present studies was to investigate potential prognostic factors, more closely related to the malignant progression of a tumor than the established markers, such as the TNM-classification system. LÄS MER

  4. 28. Minimal Residual Disease Assessment in Childhood Acute Lymphoblastic Leukemia

    Författare :Ingrid Thörn; Christer Sundström; Richard Rosenquist; Gisela Barbany; Johan Botling; Kjeld Schmiegelow; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood acute lymphoblastic leukemia; minimal residual disease; IG TCR gene rearrangements; BCR-ABL1 fusion gene transcripts; real-time quantitative PCR; multicolor flow cytometry; Pathology; Patologi; Pathology; patologi;

    Sammanfattning : Traditionally, response to treatment in hematological malignancies is evaluated by light microscopy of bone marrow (BM) smears, but due to more effective therapies more sensitive methods are needed. Today, detection of minimal residual disease (MRD) using immunological and molecular techniques can be 100 times more sensitive than morphology. LÄS MER

  5. 29. Development of New Methodology in Organic Synthesis: Lewis Acid-Mediated Rearrangements of Ammonium Ylides and Addition of 1, 3-bis(silyl) propenes to Aldehydes

    Författare :Pavel Tuzina; Peter Somfai; Ari Koskinen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; asymmetric; amino acid; ammonium ylide; Lewis acid; microwave irradiation; Organic synthesis; Organisk syntes;

    Sammanfattning : This thesis deals with the development of new methodologies in organicsynthesis. The main focus is on the development of Lewis acid-mediated [1,2]-rearrangements of ammonium ylides and the novel addition of 1,3-bis(silyl)propenes to carbonyl compounds. LÄS MER

  7. 30. Structure and mechanism on the C9H9+ and C9H9- potential energy surfaces : charge control of degenerate rearrangements and homoaromatic delocalization studied by multiple labelling with 13C and 2H, 13C NMR methods and ab initio MO calculations

    Författare :Göran Jonsäll; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER