Sökning: "precursor cells"

Visar resultat 21 - 25 av 298 avhandlingar innehållade orden precursor cells.

  1. 21. The diverse role of laminin isoforms in neuronal cells, human mast cells and blood platelets

    Författare :Wondossen Sime; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Laminins; extracellular matrix; integrins; tooth pulp fibroblasts; mast cells; megakaryocytes; platelets; cell adhesion; cell migration; neurite outgrowth;

    Sammanfattning : The close interaction of cells with other cells and with extracellular matrix (ECM) components is a prerequisite in a number of biological activities. During development of the nervous system, axons often navigate a considerable distance depending on the type of molecular factors they encounter. LÄS MER

  3. 22. DNA methylation signatures in precursor lymphoid neoplasms : with focus on clinical implications & the biology behind

    Författare :Zahra Haider; Sofie Degerman; Magnus Hultdin; Göran Roos; Pieter van Vlierberghe; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Acute Lymphoblastic Leukemia; Lymphoma; T-ALL; BCP-ALL; T-LBL; DNA methylation; CIMP; Prognosis; TAL1; HOX.;

    Sammanfattning : Precursor lymphoid neoplasms, namely acute lymphoblastic leukemias (ALL) and lymphoblastic lymphomas (LBL), are characterized by an aggressive proliferation of malignant progenitor B- or T-cells. To improve risk classification at diagnosis, better prognostic and treatment stratifying biomarkers are needed. LÄS MER

  4. 23. Neuroblastoma cells: in vitro studies on childhood cancer and amyloid precursor protein processing enzymes

    Författare :Tom Gatsinzi; Kerstin Iverfeldt; Erik Walum; Stockholms universitet; []
    Nyckelord :neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : .... LÄS MER

  5. 24. Neuronal and glial differentiation of expanded neural stem and progenitor cells; in vitro and after transplantation

    Författare :Cecilia Eriksson Linsmeier; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gtv-a; RCAS A -EGFP; transplantation; cell detection; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; GFP-actin; glial differentiation; neuronal differentiation; neurospheres; glial cultures; bFGF; EGF; cell expansion; cortical primordium; MGE; LGE; CNS; stem- progenitor cells;

    Sammanfattning : In this thesis we have used cells dissected from the lateral ganglionic eminence (LGE), the medial ganglionic eminence (MGE), and the cortical primordium of the embryonic mouse forebrain. The tissue was dissected from either i) wild-type mice, ii) green fluorescent protein (GFP)-, or iii) Gtv-a-expressing transgenic mice, and subsequently grown and expanded in vitro using two different protocols. LÄS MER

  7. 25. Transforming growth factor a in human hematopoietic cells

    Författare :Thomas M. Walz; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : TGF-a, transforming growth factor a, is a potent growth factor belonging to the family of EGF (epidermal growth factor) -related proteins. Binding to the same receptor as EGF it has a ubiquitous repertoire of target cells, including, mesenchymal, epithelial and neuronal cells. LÄS MER