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Visar resultat 1 - 5 av 298 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate

    Författare :Jens Ceder; Malmö (Abrahamsson) Urologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; somatostatin; transit amplifying cells; cell differentiation; adult stem cells; Prostate gland; prostatic benign hyperplasia; neuroendocrine cells; prostate cancer;

    Sammanfattning : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. LÄS MER

  3. 2. Assessment of precursor cell proliferation in normal and injured adult mammalian brains

    Författare :Hong Zhu; Göteborgs universitet; []
    Nyckelord :6-OHDA; astrocytes; cell proliferation; neural stem cells; ; neurogenesis; precursor cells; seizure; SVZ-OB pathway;

    Sammanfattning : In the adult mammalian brain, new neurons are generated from neural stem cells (NSCs) which reside in the subventricular zone (SVZ) of the lateral ventricle wall and in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. The biology of persistent NSCs in the adult brain is poorly understood. LÄS MER

  4. 3. Interactions between mouse CNS cells : microglia and neural precursor cells

    Författare :Johan Aarum; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aggregate cultures; cell markers; CNS; differentiation; fetal; immunohistochemistry; microglia; migration; neural stem cells; phage display; precursor; Slit.;

    Sammanfattning : The mammalian central nervous system (CNS) contains a variety of cells, all specialized to perform different functions. Most numerous are the three types of glia cells, whose basic role is to support the signaling units of the CNS, the neurons. LÄS MER

  5. 4. Molecular specification of expanded forebrain neural stem and progenitor cells

    Författare :Malin Parmar; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratology; ontogeny; embryology human ; Development biology; developmental control genes; in vitro expansion; transplantation; precursor cell; stem cells; progenitor cell; human; mouse; Utvecklingsbiologi; teratologi; embryologi människa ;

    Sammanfattning : The molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. LÄS MER

  7. 5. Regulatory properties of dendritic cells and B cells in adaptive immunity

    Författare :Bengt Johansson Lindbom; Adaptivt immunförsvar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; Cellular differentiation; Cytokines; Dendritic cells; B lymphocytes; T lymphocytes;

    Sammanfattning : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. LÄS MER