Sökning: "pharmaceutical production"

Visar resultat 6 - 10 av 108 avhandlingar innehållade orden pharmaceutical production.

  1. 6. A supercritical fluids extraction process for the production of drug loaded biodegradable microparticles

    Författare :Raouf Ghaderi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : The purpose of this thesis was to develop methods suitable for the incorporation of drug substancessuch as proteins into microparticles intended for controlled release. In particular a novel techniquefor the preparation of microparticles using supercritical fluids was investigated. LÄS MER

  3. 7. Integrated Product and Process Design for Mass Customization: A Road Towards Patient Access to Individualized Pharmaceutical Therapy

    Författare :Rydvikha Govender; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hot melt extrusion; mass customization; modularization; integration; fused deposition modelling; individualized therapy; pharmaceutical manufacturing; reconfiguration; polymeric solid dispersion; patient-centric product design;

    Sammanfattning : Individualized pharmaceutical therapy strives to attain optimal health outcomes a priori in all patients treated with pharmaceutical products by tailoring these products to each patient’s holistic needs. However, existing mass-produced pharmaceutical products are not available in sufficient variety to enable adequate tailoring to the diverse needs of individuals. LÄS MER

  4. 8. Exploring Pharmaceutical Mass Customization

    Författare :Maria Daniela Irene Siiskonen; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mass customization; pharmaceutical product customization; postponement; product modularization; process flexibility;

    Sammanfattning : The core purpose of therapeutic pharmaceutical products is to induce responses to various diseases in patients and thereby bring societal value; however, unmet medical needs currently prevail. Conventional treatment of these products predominantly embraces a one-size-fits-all design and is manufactured in a mass-production context. LÄS MER

  5. 9. Testing Pills, Enacting Obesity : The work of localizing tools in a clinical trial

    Författare :Petra Jonvallen; Boel Berner; Claes-Fredrik Helgesson; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Invisible work; contract research organisation; standardization; articulation work; production tasks; enactment; evidence based medicine; clinical trials; clinical research protocol; rationalizing tools; obesity; pharmaceutical production; clinical practice; medicalisation; Övervikt; klinisk prövning; Technology and social change; Teknik och social förändring; Genus och teknik;

    Sammanfattning : This study examines tools and practices involved in a large scale and multi-sited clinical trial of a potential drug against obesity. Two tools are in focus: a clinical research protocol and a computer control system. LÄS MER

  7. 10. 3D printing of lipid-based formulations into personalized solid oral dosage forms

    Författare :Jenny Johannesson; Christel Bergström; Alexandra Teleki; Mattias Paulsson; Maria Strömme; Abdul Basit; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; poorly water-soluble drug; lipid-based formulation; Pickering emulsion; emulsion gel; semi-solid extrusion; 3D printing; lipid tablet; personalized dosage form; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The pharmaceutical development process starts with patient populations and their unmet therapeutic needs. Traditional pharmaceutical manufacturing of solid oral dosage forms is based on the strategy of one-size-fits-all. This is problematic, especially for patient populations with high patient-to-patient variability, as in pediatrics. LÄS MER