Sökning: "individualized therapy"

Visar resultat 1 - 5 av 72 avhandlingar innehållade orden individualized therapy.

  1. 1. Integrated Product and Process Design for Mass Customization: A Road Towards Patient Access to Individualized Pharmaceutical Therapy

    Författare :Rydvikha Govender; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hot melt extrusion; mass customization; modularization; integration; fused deposition modelling; individualized therapy; pharmaceutical manufacturing; reconfiguration; polymeric solid dispersion; patient-centric product design;

    Sammanfattning : Individualized pharmaceutical therapy strives to attain optimal health outcomes a priori in all patients treated with pharmaceutical products by tailoring these products to each patient’s holistic needs. However, existing mass-produced pharmaceutical products are not available in sufficient variety to enable adequate tailoring to the diverse needs of individuals. LÄS MER

  3. 2. Optimization of first-line anti-tuberculosis therapy in patients co-infected with HIV

    Författare :Jesper Sundell; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; HIV; Pharmacokinetics; Pharmacogenetics; LC-MS MS; Individualized therapy;

    Sammanfattning : Every year over one million people die from tuberculosis. People infected with HIV are significantly more vulnerable to tuberculosis, which is the leading cause of HIV-associated death. The first-line treatment for tuberculosis consists of rifampicin, isoniazid, pyrazinamide and ethambutol. LÄS MER

  4. 3. Treating depression and its comorbidity : From individualized Internet-delivered cognitive behavior therapy to affect-focused psychodynamic psychotherapy

    Författare :Robert Johansson; Gerhard Andersson; Per Carlbring; Pim Cuijpers; Jacques Barber; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Depression; comorbidity; psychological treatment; psychotherapy; Internet; Internet-delivered treatment; cognitive behavior therapy; psychodynamic psychotherapy; Depression; komorbiditet; psykologisk behandling; psykoterapi; Internet; internetbaserad behandling; kognitiv beteendeterapi; psykodynamisk psykoterapi;

    Sammanfattning : The overarching goal of this thesis has been to enhance Internet-delivered psychological treatments for depression and its comorbidity. To this end, three randomized controlled trials (Study II, III and IV) with a total of 313 participants were conducted. LÄS MER

  5. 4. Tailoring Radionuclide Therapy of Neuroendocrine Tumors - Bridging the Gaps

    Författare :Anna Sundlöv; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; PRRT; somatostatin analogs; pituitary function; renal function; dosimetry; 68Ga-DOTATATE; individualized treatment; neuroendocrine tumors;

    Sammanfattning : Background and Aims: Radionuclide therapy is systemic, targeted radiotherapy. As such, we can apply the basic principles of radiobiology used in everyday practice in radiation oncology, as a means of tailoring the treatment to each patient and optimizing the balance between efficacy and toxicity. LÄS MER

  7. 5. Stimulation of tendon repair by platelet concentrate, CDMP-2 and mechanical loading in animal models

    Författare :Olena Virchenko; Per Aspenberg; Jon Karlsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Achilles tendon; injuries; physiology; Blood platelets; tendon injuries; physiopathology; therapy; wound healing; Orthopaedics; Ortopedi;

    Sammanfattning : Growth factor delivery may be useful to accelerate the rate of tendon healing. We studied Platelet Concentrate, which in effect can be regarded as a cocktail of growth factors relevant for tendon healing. LÄS MER