Sökning: "Mattias Paulsson"

Hittade 2 avhandlingar innehållade orden Mattias Paulsson.

  1. 1. Controlled Release Gel Formulations for Mucosal Drug Delivery

    Författare :Mattias Paulsson; David Attwood; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; Galenisk farmaci; Pharmaceutics;

    Sammanfattning : Drug delivery to nasal or ocular mucosa for either local or systemic action faces many obstacles – these routes are protected by effective mechanisms. Gel formulations with suitable rheological and mucoadhesive properties increase the contact time at the site of absorption. LÄS MER

  3. 2. 3D printing of lipid-based formulations into personalized solid oral dosage forms

    Författare :Jenny Johannesson; Christel Bergström; Alexandra Teleki; Mattias Paulsson; Maria Strömme; Abdul Basit; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; poorly water-soluble drug; lipid-based formulation; Pickering emulsion; emulsion gel; semi-solid extrusion; 3D printing; lipid tablet; personalized dosage form; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The pharmaceutical development process starts with patient populations and their unmet therapeutic needs. Traditional pharmaceutical manufacturing of solid oral dosage forms is based on the strategy of one-size-fits-all. This is problematic, especially for patient populations with high patient-to-patient variability, as in pediatrics. LÄS MER