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Visar resultat 6 - 8 av 8 avhandlingar som matchar ovanstående sökkriterier.
6. LL-37-derived cyclic antimicrobial drug leads : Design, synthesis, activity and different ways of creating them
Sammanfattning : In an era where last-line antibiotics are failing, one of the powerful approaches to develop novel therapeutic agents is to turn back to nature in order to identify possible drug candidates. Among the potential candidates, antimicrobial peptides (AMPs) have garnered much attention as an antimicrobial. LÄS MER
7. Effects of ionising and non-ionising radiation in cell systems and a rat model for immuno-therapy
Sammanfattning : The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. LÄS MER
8. Mechanisms of formation and protection against oxidative DNA damage in vitro and in vivo
Sammanfattning : Oxidative DNA damage has been linked to cancer and aging as well as other diseases. The aim of this thesis was to study the mechanisms for DNA damage generated in cells or in vitro systems by ionizing radiation or transition metals like iron ions. LÄS MER