Sökning: "Wang Guangshun"

Hittade 1 avhandling innehållade orden Wang Guangshun.

  1. 1. LL-37-derived cyclic antimicrobial drug leads : Design, synthesis, activity and different ways of creating them 

    Författare :Taj Muhammad; Ulf Göransson; Sunithi Gunasekera; Adam A. Strömstedt; Wang Guangshun; Uppsala universitet; []
    Nyckelord :antimicrobial peptide; host defense; antimicrobial; LL-37; KR-12; peptide cyclisation; peptide dimerisation; croos-linking; cyanobactin-macrocyclase; PatGmac; butelase 1; enzymatic cyclisation; immobilisation; Farmakognosi; Pharmacognosy;

    Sammanfattning : In an era where last-line antibiotics are failing, one of the powerful approaches to develop novel therapeutic agents is to turn back to nature in order to identify possible drug candidates. Among the potential candidates, antimicrobial peptides (AMPs) have garnered much attention as an antimicrobial. LÄS MER