Sökning: "påhlman"

Visar resultat 16 - 20 av 21 avhandlingar innehållade ordet påhlman.

1. 16. Acute Abdominal Pain

   Författare :Helena Laurell; Ulf Gunnarsson; Lars-Erik Hansson; Lars Påhlman; Rune Sjödahl; Uppsala universitet; []
   Nyckelord :Surgery; acute abdominal pain; diagnostic pitfalls; decision-making; competence; sensitivity; specificity; high age; acute appendicitis; Kirurgi;

   Sammanfattning : The aim was to identify diagnostic difficulties for acute abdominal pain at the emergency department and during hospital stay. A total of 3349 patients admitted to Mora Hospital with acute abdominal pain of up to seven days duration, were registered prospectively for history and clinical signs according to a structured schedule. LÄS MER

3. 17. RUNX1/AML1 functions and mechanisms regulating granulocyte-macrophage colony-stimulating factor transcription

   Författare :Hebin Liu; Sven Påhlman; Umeå universitet; []
   Nyckelord :RUNX1 AML1; Granulocyte-macrophage colony-stimulating factor GM-CSF ; Calcineurin; CaMKII; Ets1; Transforming growth factor-b TGF-b ; Smad3; molekylärbiologi; Molecular Biology;

   Sammanfattning : Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine involved in the production and function of hematopoietic cells, and GM-CSF plays in particular a major role in responses to infection and physiological and pathological inflammatory processes. GM-CSF is produced in many cell types, and increases in the intracellular Ca2+ concentration are, like in many other systems, of major importance in the intracellular signaling that determines GM-CSF expression after receptor stimulation of the cells. LÄS MER

4. 18. Rectal cancer surgery : Defunctioning stoma, anastomotic leakage and postoperative monitoring

   Författare :Peter Matthiessen; Olof Hallböök; Rune Sjödahl; Lars Påhlman; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anterior resection of the rectum; total mesorectal excision; TME; anastomotic leakage; defunctioning stoma; risk factors; intraoperative adverse events; population based study; postoperative monitoring; CT-scan microdialysis; cytokines; Surgery; Kirurgi;

   Sammanfattning : The understanding of the mesorectal spread in rectal cancer has lead to wide acceptance of total mesorectal excision (TME) as the surgical technique of choice for carcinoma in the lower and mid rectum. While oncological results and survival have improved with TME-surgery, morbidity and mortality remain important issues. LÄS MER

5. 19. Inhibition of PDGF receptor signaling in tumor stroma : Effects on interstitial hypertension, drug uptake and therapeutic response

   Författare :Kristian Pietras; Sven Påhlman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; PDGF; tumor; stroma; tyrosine kinase inhibitor; combination therapy; Onkologi; Oncology; Onkologi; molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : The role of platelet-derived growth factor (PDGF) in malignancies involves both autocrine and paracrine stimulation of cells within the tumor. The interstitial fluid pressure (IFP) is one of the forces that govern the transvascular flow of fluids. LÄS MER

7. 20. Optimising Radiotherapy in Rectal Cancer Patients

   Författare :Calin Radu; Bengt Glimelius; Åke Berglund; Lars Påhlman; Ragnar Hultborn; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal cancer; locally advanced; radiotherapy; FDG-PET; peripheral boost; protons; quality-of-life; Oncology; Onkologi;

   Sammanfattning : Rectal cancer is the eight most common cancer diagnosis in Sweden in both men and women, with almost 2000 new cases per year. Radiotherapy, which is an important treatment modality for rectal cancer, has evolved during the past decades. LÄS MER