Sökning: "ovulation induction"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden ovulation induction.

  1. 1. Chemotactic factors in the human follicle at ovulation

    Författare :Eva Runesson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokine; follicle; gonadotropin; human; ovary; ovulation;

    Sammanfattning : Ovulation is initiated by the midcycle gonadotropin surge, which leads to a controlled degradation of the follicle wall ending in follicular rupture and oocyte extrusion. The gonadotropins triggers several biochemical and biophysical changes such as vascular alterations, increased proteolytic enzyme activity and leukocyte extravasation, within the preovulatory follicle. LÄS MER

  3. 2. Granulosa cell apoptosis: Transcriptional regulation by the nuclear progesterone receptor

    Författare :P. Anders Friberg; Göteborgs universitet; []
    Nyckelord :ovary; granulosa cells; ovulation; luteinization; progesterone; apoptosis; cholesterol synthesis; isoprenylation;

    Sammanfattning : Ovarian follicle atresia caused by granulosa cell apoptosis is a central process in normal female physiology. Progesterone has been reported to be a survival factor in granulosa cells at several developmental stages. LÄS MER

  4. 3. Endocrine and therapeutic aspects of infertile women with the polycystic ovary syndrome

    Författare :Margareta Fridström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cost-effectiveness; FSH threshold; glucocorticoids; granulosa cells; infertility; in vitro fertilisation; obesity; ovulation induction; polycystic ovary syndrome; pregnancy complications;

    Sammanfattning : Fertility treatment with gonadotrophins in infertile clomiphene resistant women with the polycystic ovary syndrome (PCOS) is troublesome with an unpredictive ovarian response. The purpose of this study was to elucidate aspects of ovarian sensitivity and to evaluate treatment efficiency and costs of ovulation induction (OI) and in vitro fertilisation (IVF), as well as pregnancy outcome after infertility treatment in patients with PCOS. LÄS MER

  5. 4. Intraovarian regulators of the ovulatory process. Studies in the rat and human

    Författare :Marita E. Pall; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : LH stimulation of the preovulatory follicle results in extensive biochemical and morphological changes which lead to follicle rupture. Many redundant and parallel functioning mediator systems are involved in this process. LÄS MER

  7. 5. Expression, regulation and fuction of small ubiquitin-related modifier-1. Interaction with nuclear proteins in vivo

    Författare :Linus Ruijin Shao; Göteborgs universitet; []
    Nyckelord :SUMO-1; LH receptor; PR isoforms; caspase-3; DNA fragmentation; apoptosis; granulosa cells; HIF-1alpha; hypoxia; brain and heart;

    Sammanfattning : The small ubiquitin-related modifier-1 (SUMO-1) is a 101-amino acid, ~12 kDa protein that is 18% identical to ubiquitin. Posttranslational covalent tagging of proteins with SUMO-1 (SUMOylation) serves many functions. For example, regulation of protein stability and modulation of transcriptional activation. LÄS MER