Sökning: "P. Anders Friberg"

Hittade 3 avhandlingar innehållade orden P. Anders Friberg.

  1. 1. Granulosa cell apoptosis: Transcriptional regulation by the nuclear progesterone receptor

    Författare :P. Anders Friberg; Göteborgs universitet; []
    Nyckelord :ovary; granulosa cells; ovulation; luteinization; progesterone; apoptosis; cholesterol synthesis; isoprenylation;

    Sammanfattning : Ovarian follicle atresia caused by granulosa cell apoptosis is a central process in normal female physiology. Progesterone has been reported to be a survival factor in granulosa cells at several developmental stages. LÄS MER

  3. 2. Study Design and Dose Regimen Evaluation of Antibiotics based on Pharmacokinetic and Pharmacodynamic Modelling

    Författare :Anders Kristoffersson; Lena Friberg; Mats Karlsson; Pernilla Lagerbäck; Otto Cars; Stephan Schmidt; Uppsala universitet; []
    Nyckelord :pharmacometric; optimal design; pharmacokinetics; pharmacodynamics; PKPD; resistance; antibiotics; modeling; time-kill curve; colistin; meropenem; ciprofloxacin; non-linear mixed effects models; bayesian; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Current excessive use and abuse of antibiotics has resulted in increasing bacterial resistance to common treatment options which is threatening to deprive us of a pillar of modern medicine. In this work methods to optimize the use of existing antibiotics and to help development of new antibiotics were developed and applied. LÄS MER

  4. 3. Towards the Limits – Climate Change Aspects of Life and Health in Northern Sweden : studies of tularemia and regional experiences of changes in the environment

    Författare :Maria Furberg; Maria Nilsson; Anders Johansson; Lars Weinehall; Peter Friberg; Umeå universitet; []
    Nyckelord :Climate change; public health; Indigenous peoples; Sami; reindeer herding; resilience; tularemia; mixed-methods; infectious disease; seroprevalence; ELISA; outbreak investigation; risk factor; ecology; Francisella tularensis; Epidemiology; epidemiologi; folkhälsa; Public health;

    Sammanfattning : BackgroundIndigenous peoples with traditional lifestyles worldwide are considered particularly vulnerable to climate change effects. Large climate change impacts on the spread of infectious vector-borne diseases are expected as a health outcome. LÄS MER