Sökning: "caspase-3"

Visar resultat 1 - 5 av 124 avhandlingar innehållade ordet caspase-3.

  1. 1. Caspase-3 in lens epithelium

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Nooshin Talebizadeh; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ultraviolet radiation; caspase-3; lens; cataract; apoptosis; Immunohistochemistry; spatial distribution; time evolution; modelling; automatic analysis; cell counting; image analysis.; Ophtalmology; Oftalmiatrik;

    Sammanfattning : Purpose: To model the time evolution of active caspase-3 protein expression in a healthy lens, and in a lens exposed to UVR-300 nm (UVR-B). To develop an automated method to classify the fluorescent signal of biomarkers in the lens epithelial cells.Methods: Six-week old Sprague-Dawley rats were used. LÄS MER

  2. 2. Bioactivity of Medicinal Bolivian Andean plants. Effects on cell proliferation and related processes

    Detta är en avhandling från Lund University

    Författare :Gloria Rodrigo; Lunds universitet.; Lund University.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bolivian medicinal plants; colon cancer; cell proliferation; DNA synthesis; apoptosis; caspase-3; sesquiterpene; curcuphenol; damsin; coronopilin;

    Sammanfattning : Popular Abstract in English Bolivia is the seventh richest country regarding biodiversity in the world. Also, in its territory more than 36 indigenous nations co-exist. Each of these has traditional medicines that are passed on from generation to generation orally. It has been estimated that the Bolivian flora has more than 20,000 plant species. LÄS MER

  3. 3. Fetal Outcome in Experimental Diabetic Pregnancy

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sheller Zabihi; Uppsala universitet.; [2008]
    Nyckelord :Cell biology; Rat; Mouse; TG; KO; Diabetes in Pregnancy; Embryo; Folic acid; Superoxide dismutase; Catalase; Glutathione peroxidase; Vascular endothelial growth factor-A; Folate binding protein-1; Bax; Bcl-2; Caspase-3; P53; Pax-3; Blood flow; Cellbiologi;

    Sammanfattning : Women with pregestational diabetes have a 2-5 fold increased risk of giving birth to malformed babies compared with non-diabetic women. Diabetes-induced oxidative stress in maternal and embryonic tissues has been implicated in the teratogenic process. LÄS MER

  4. 4. Tissue-Selective Activation and Toxicity of Substituted Dichlorobenzenes Studies on the Mechanism of Cell Death in the Olfactory Mucosa

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anna Franzén; Uppsala universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; tissue-selective toxicity; bioactivation; olfactory mucosa; substituted dichlorobenzenes; Bowman s glands; sustentacular cells; ER stress; Grp78; caspase-12; caspase-3; CYP2A5; protein adduction; nasal toxicity; Toxikologi; PHARMACY Toxicology; FARMACI Toxikologi;

    Sammanfattning : The nasal passages are constantly exposed to both air- and bloodborne foreign compounds. In particular, the olfactory mucosa is demonstrated to be susceptible to a variety of drugs and chemicals. LÄS MER

  5. 5. Genetic studies of neuroblastoma with emphasis on the apoptotic pathway

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Frida Abel; Göteborgs universitet.; Gothenburg University.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; child; cancer; neuroectodermal; neural crest; loss of heterozygosity; LOH; bcl-2; mcl-1; apaf-1; caspase-2; caspase-3; caspase-9; PIN; DLC-1;

    Sammanfattning : Aim: The objective of this thesis was to find genes and chromosomal regions involved in neuroblastoma (NB) tumor progression. NB is a childhood tumor of the sympathetic nervous system that generally occurs spontaneously. LÄS MER