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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Targeting polo-like kinase 1 in pediatric leukemia

   Författare :Oksana Goroshchuk; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Acute lymphoblastic leukemia (ALL) is one of the most common cancers among children in the world, with almost 90% complete remission rate after the primary treatment. However, some patients are resistant to treatment and some relapse later. Moreover, existing treatments are toxic and induce life-long adverse effects. LÄS MER

3. 2. Product-service systems: Panacea or myth?

   Författare :Oksana Mont; Internationella miljöinstitutet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; economic systems; economic policy; Nationalekonomi; ekonometri; ekonomisk teori; ekonomiska system; ekonomisk politik; Production technology; Produktionsteknik; economic theory; econometrics; Economics; communal washing centres.; car sharing; systems for sharing power tools and garden-care equipment; product policy; drivers and barriers for companies; servicising; life cycle thinking; Product-service systems; functional thinking;

   Sammanfattning : Life cycle environmental problems have been addressed by a number of strategies. However, the results are mostly lamentable because solutions are searched for within the same paradigms that give rise to the problems. LÄS MER

4. 3. Science-policy interaction in the governance of complex socio-ecological risks : The case of chemicals management in the Baltic Sea

   Författare :Oksana Udovyk; Michael Gilek; Johan Hedrén; Sivlio Funtowicz; Södertörns högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Risk; Uncertainty; MSFD; HELCOM; REACH; post-normal science; precautionary; participation; Östersjö- och Östeuropaforskning; Baltic and East European studies;

   Sammanfattning : In this thesis, I examine knowledge production and science-policy interaction associated with the management of chemical substances in the Baltic Sea under conditions of uncertainty and complexity. The thesis is primarily based on a qualitative analysis of policy documents and reports produced by the European Union (EU), the Helsinki Commission, the Swedish Chemicals Agency, and Gothenburg municipality, as well as 30 semi-structured interviews with scientific experts, policy makers, and government officials with knowledge and working experience in the relevant policy arenas. LÄS MER

5. 4. Cryogels Based on Crosslinked Cells as Green Biocatalysts for Biotechnology

   Författare :Oksana Zaushitsyna; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cells; Crosslinkers; PVA PEI; Immobilization; Biocatalysts; Biobased chemicals; Biotransformation; stress tolerance;

   Sammanfattning : Abstract Due to the finite nature of fossil resources and their environmental impact, such as greenhouse gases and climate change, the bio-based production of chemicals, materials and fuels is the subject of extensive research in industrial biotechnology. Biotransformation and fermentation are considered to be mild, “green” processes that make use of effective and reliable biocatalysts to provide bio-based chemicals. LÄS MER

7. 5. Structure and Dynamics of Core-Excited Species

   Författare :Oksana Travnikova; Maria Novella Piancastelli; Svante Svensson; Denis Ceolin; Pascal Lablanqui; Uppsala universitet; []
   Nyckelord :Physics; Synchrotron radiation; X-ray Photoelectron Spectroscopy XPS ; X-ray Absorption Spectroscopy XAS ; Resonant Auger Spectroscopy RAS ; Auger Electron Spectroscopy AES ; Energy-Selected Auger Electron PhotoIon COincidence ES-AEPICO ; core excitation; core ionization; linear free energy relationships LFER ; molecular-field splitting; substituent effects; nuclear dynamics; isomerization; Cl2; N2O; methane derivatives; allene; acetylacetone; Fysik;

   Sammanfattning : In this thesis we have performed core-electron spectroscopy studies of gas phase molecular systems starting with smaller diatomic, continuing with triatomic and extending our research to more complex polyatomic ones. We can subdivide the results presented here into two categories: the first one focusing on electronic fine structure and effect of the chemical bonds on molecular core-levels and the other one dealing with nuclear dynamics induced by creation of a core hole. LÄS MER